Biochemical variables from Holstein-Friesian calves older than one week are comparable to those obtained from adult animals of stable metabolic status on the same farm
Biochemical variables from Holstein-Friesian calves older than one week are comparable to those obtained from adult animals of stable metabolic status on the same farm
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DOI：
10.1111/vcp.12218
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发表时间：
2015-03-01
影响因子：
1.2
通讯作者：
Abuelo, Angel
中科院分区：
文献类型：
--
作者：
Perez-Santos, Maria;Castillo, Cristina;Abuelo, Angel
背景牛的血液变量的变化以前曾有报道。一些研究调查了差异，随着时间的推移，使用repeatmeasures.ObjectivesThe目的的研究是调查的变化，在选择变量在第一个3 months的生活Holstein-Friesian小牛使用repeatsampling.MethodsTwenty健康小牛出生当天（0），并在6，13，21，30，60，和90天的生活。分析变量包括葡萄糖、总蛋白、白蛋白、尿素和肌酐浓度，以及AST、GGT和CK活性。使用特定的计算机软件从40头成年母牛获得参考区间（RI）。在整个研究期间，每个分析物的变化和差异相对于成年牛RI进行了assessed.ResultsWith葡萄糖的例外，所研究的变量受小牛的年龄。然而，对于研究的大多数分析物，从1周龄起小牛获得的值仍在成年牛中测定的RI范围内。在小牛的第一个星期的生活，一些变量以外的成年牛的RI是由于出生和初乳intake.ConclusionsWith AST和GGT活性的变化，RI为标准的生化变量确定的成年牛可能是有效的小牛年龄超过一周。然而，对于出生后第一周内的小牛，需要特别考虑。
BackgroundAge-related changes in blood variables have previously been reported for cattle. A few studies have investigated differences in biochemistry analytes over time using repeat measures.ObjectivesThe purpose of the study was to investigate the variation in select variables during the first 3months of life of Holstein-Friesian calves using repeat sampling.MethodsTwenty healthy calves were sampled on the day of birth (0) and at 6, 13, 21, 30, 60, and 90days of life. Analyzed variables included concentration of glucose, total protein, albumin, urea and creatinine, and activity of AST, GGT, and CK. Reference intervals (RI) were obtained from 40 adult cows using specific computer software. The variation in each analyte throughout the study period and differences relative to the RI in adult cattle were assessed.ResultsWith the exception of glucose, the studied variables were affected by the calf's age. However, for most of the analytes studied, the values obtained from calves from one week of age onwards remained within the RI determined in adult cattle. During the calves' first week of life, some variables outside the RI of adult cattle were due to the changes associated with birth and colostrum intake.ConclusionsWith the exception of AST and GGT activity, RI for standard biochemistry variables determined for adult cattle are likely to be valid for calves older than one week. However, special consideration is necessary for calves within their first week of life.