Personal experience in lung cancer sleeve lobectomy and sleeve pneumonectomy
Personal experience in lung cancer sleeve lobectomy and sleeve pneumonectomy
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DOI：
10.1016/s0003-4975(02)03524-5
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发表时间：
2002-06-01
影响因子：
4.6
通讯作者：
Meda, S
中科院分区：
文献类型：
--
作者：
Mezzetti, M;Panigalli, T;Meda, S
背景袖状肺叶切除术（SL）和气管袖状肺切除术（TSP）是治疗气道良性和恶性疾病的标准切除术的有价值的替代技术，并允许保留肺实质。从1979年到1999年，米兰大学胸外科对非小细胞肺癌进行了83例袖状肺叶切除术和27例气管袖状全肺切除术。其中右上叶切除46例，中上叶切除11例，左上叶切除18例，左下叶切除8例，右肺切除27例。SL组死亡率为3.6%，TSP组为7.4%。并发症占所有SL的10.8%，占所有TSP的15%。SL和TSP的5年总生存率分别为43%和20%; 10年生存率分别为34%和14%。NO和N1-N2疾病患者的生存率有显著差异。袖状肺叶切除术是一种适当的外科手术，在情况允许的情况下，可替代肺切除术治疗呼吸储备有限的患者。气管袖状全肺切除术并发症多，生存率低。
Background. Sleeve lobectomy (SL) and tracheal sleeve pneumonectomy (TSP) represent valuable alternative techniques to standard resections in the treatment of benign and malignant conditions of the airway and allow preservation of lung parenchyma.Methods. Eighty-three sleeve lobectomies and 27 tracheal sleeve pneumonectomies have been performed for nonsmall cell lung cancer in the thoracic department of the University of Milan from 1979 to 1999. There were 46 upper right lobectomies, 11 upper and middle lobectomies, 18 upper left lobectomies, 8 lower left lobectomies, and 27 right pneumonectomies.Results. Mortality rate was 3.6% in SL and 7.4% in TSP. Complications were 10.8% of all SLs and 15% of all TSPs. The overall 5-year survival rate was 43% for SL and 20% for TSP; the 10-year survival rate was 34% and 14%, respectively. There was a highly significant difference in survival between patients with NO and N1-N2 disease.Conclusions. Sleeve lobectomy is an appropriate surgical procedure and an alternative to pneumonectomy in patients with limited respiratory reserve whenever the situation permits. Trachael sleeve pneumonectomy is associated with more complications and poor survival.