Cell proliferation in follicle-associated epithelium of mouse Peyer's patch.
Cell proliferation in follicle-associated epithelium of mouse Peyer's patch.
复制标题
小鼠派尔氏淋巴结滤泡相关上皮细胞增殖。
作者：
M. Smith;L. G. Jarvis;I. King
来自小鼠派尔集合淋巴结的滤泡相关上皮（FAE）由含有杯状上皮细胞以及柱状上皮细胞的圆顶部分和含有潘氏上皮细胞以及杯状上皮细胞和未分化上皮细胞的隐窝部分组成。FAE中柱状上皮、杯状细胞和潘氏细胞的比例与正常隐窝/绒毛复合体中的比例相似。有丝分裂仅限于FAE的隐窝。FAE柱状上皮细胞的细胞更新时间，估计从实验使用氚化胸苷，是大约60小时。大量的淋巴样细胞也存在于FAE中，特别是在远离隐窝的区域。卵泡相关和绒毛上皮结构之间的相似性进行了讨论，连同其可能的相关性，以“M”细胞内的FAE的形成。
Follicle-associated epithelium (FAE) from the mouse Peyer's patch consists of a dome part containing goblet as well as columnar epithelial cells and a crypt part, containing Paneth as well as goblet and undifferentiated epithelial cells. The proportions of columnar epithelial, goblet and Paneth cells in the FAE are similar to those found in normal crypt/villus complexes. Mitosis is confined to the crypts of the FAE. The cell-renewal time for FAE columnar epithelial cells, estimated from experiments using tritiated thymidine, is approximately 60 hours. Large numbers of lymphoid cells are also present in the FAE, particularly in regions distal to the crypts. The similarity between follicle-associated and villus epithelial structure is discussed, together with its possible relevance to "M" cell formation within the FAE.