Immunotherapy in food allergy.
Immunotherapy in food allergy.
复制标题
DOI：
10.2217/imt.10.15
复制
发表时间：
2010-05
期刊：
影响因子：
2.8
通讯作者：
Bryce PJ
中科院分区：
文献类型：
--
作者：
Kamdar T;Bryce PJ
Food allergies are caused by immune responses to food proteins and represent a breakdown of oral tolerance. They can range from mild pruritis to life-threatening anaphylaxis. The only current consensus for treatment is food avoidance, which is fraught with compliance issues. For this reason, there has been recent interest in immunotherapy, which may induce desensitization and possibly even tolerance. Through these effects, immunotherapy may decrease the potential for adverse serious reactions with accidental ingestions while potentially leading to an overall health benefit. In this review, we discuss the mechanisms of food allergy and give an overview of the various immunotherapeutic options and current supporting evidence, as well as look towards the future of potential novel therapeutic modalities.
