Facile Syntheses of 3-Hydroxyflavones

Facile Syntheses of 3-Hydroxyflavones
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DOI:
10.1021/ol300310e
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发表时间:
2012-03-16
期刊:
影响因子:
5.2
通讯作者:
Ozturk, Turan
Ozturk, Turan
中科院分区:
化学1区
文献类型:
--
作者:
Gunduz, Simay;Goren, Ahmet C.;Ozturk, Turan

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改进了现有的合成方法,使3-羟基黄酮的合成反应时间缩短,纯化简单,产率提高。该方法的应用提供了在一个步骤中合成在苯环(环B)上具有羟基的3 HF,这与使用文献中可用的当前方法的四个步骤、长反应时间和低收率相比是一种改进。
Modification of the present synthetic methods led to the syntheses of 3-hydroxyflavones in a shorter reaction time, with simple purification and higher yields. Application of the method provided the syntheses of 3HFs having a hydroxyl group on the phenyl ring (ring B) in one step, which is an improvement compared to the four steps, long reaction time, and low yield using the current method available in the literature.