Magnetic resonance imaging abnormalities of peripheral nerve and muscle are common in amyotrophic lateral sclerosis and share features with multifocal motor neuropathy.
Magnetic resonance imaging abnormalities of peripheral nerve and muscle are common in amyotrophic lateral sclerosis and share features with multifocal motor neuropathy.
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DOI：
10.1002/mus.24630
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发表时间：
2015-07
期刊：
影响因子：
3.4
通讯作者：
Howe, Benjamin M.
中科院分区：
文献类型：
--
作者：
Staff, Nathan P.;Amrami, Kimberly K.;Howe, Benjamin M.
ALS患者的周围神经和肌肉MRI可用于研究其他诊断，包括多灶性运动神经病（MMN）。在这些情况下，周围神经和肌肉的MRI表现没有得到很好的描述，使得结果的解释变得困难。我们系统地检查了ALS（n=60）和MMN（n=8）患者的周围神经和肌肉MRI表现。在ALS和MMN患者中，MRI异常很常见（分别为85%和75%），但与疾病严重程度无关。周围神经MRI异常的频率相似（ALS：58% vs. MMN：63%），大多数变化的严重程度为轻度至中度。肌肉MRI变化在ALS中更常见（57% vs. 33%），MMN患者中未观察到肌肉萎缩。ALS和MMN的周围神经和肌肉MRI异常是常见的，并具有某些共同特征。
MRI of peripheral nerve and muscle in patients with ALS may be performed to investigate alternative diagnoses including multifocal motor neuropathy (MMN). MRI findings of peripheral nerve and muscle are not well described in these conditions, making interpretation of results difficult. We examined systematically the peripheral nerve and muscle MRI findings in patients with ALS (n=60) and MMN (n=8). In patients with ALS and MMN, abnormal MRIs were common (85% and 75%, respectively) but did not correlate with disease severity. Peripheral nerve MRI abnormalities were similar in frequency (ALS: 58% vs. MMN: 63%) with most changes being of mild-to-moderate severity. Muscle MRI changes were more common in ALS (57% vs. 33%), and no muscle atrophy was seen in patients with MMN. MRI abnormalities of peripheral nerve and muscle in ALS and MMN are common and share some features.
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影响因子：
4.1
作者：
Du, Rose;Auguste, Kurtis I.;Weinstein, Philip R.
通讯作者：
Weinstein, Philip R.
影响因子：
--
作者：
Young, Nathan P.;Laughlin, Ruple S.;Sorenson, Eric J.
通讯作者：
Sorenson, Eric J.
影响因子：
9.9
作者：
VanEs, HW;VandenBerg, LH;Wokke, JHJ
通讯作者：
Wokke, JHJ
影响因子：
11.2
作者：
DYCK, PJ;SHERMAN, WR;SWANSON, CJ
通讯作者：
SWANSON, CJ