Management of hepatitis B and C infections in rheumatologic disease
Management of hepatitis B and C infections in rheumatologic disease
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DOI：
10.1016/j.berh.2019.04.001
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发表时间：
2018-12-01
影响因子：
5.2
通讯作者：
Marks, Kristen M.
中科院分区：
文献类型：
--
作者：
Cheah, Jonathan T. L.;Faragon, John J.;Marks, Kristen M.
乙型和丙型肝炎病毒在风湿病中作为病因和重要的合并症存在双重考虑，必须加以评估和解决。本文综述了乙型肝炎与关节炎、结节性多动脉炎、丙型肝炎与关节炎、Sicca综合征和冷球蛋白性血管炎的关系。最近的数据有关抗病毒管理在这些条件下，特别是关于使用直接作用的抗病毒药物在丙型肝炎，也提出。此外，还讨论了在全身性炎症性风湿病的背景下，作为合并症的乙型和丙型肝炎的检测和治疗指南以及改善疾病的抗风湿病治疗的使用。(C) 2019 Elsevier Ltd.版权所有。
Hepatitis B and C viruses present dual considerations in rheumatic disease as both etiologic factors and important comorbidities that must be assessed and addressed. This review summarizes the link between hepatitis B and arthritis and polyarteritis nodosa as well as hepatitis C and arthritis, Sicca syndrome and cryoglobulinemic vasculitis. Recent data pertaining to the antiviral management in these conditions, especially regarding the use of the direct-acting antivirals in hepatitis C, are also presented. Additionally, guidance on testing and treatment of hepatitis B and C as comorbidities in the context of systemic inflammatory rheumatic conditions and the use of disease-modifying antirheumatic therapy are discussed. (C) 2019 Elsevier Ltd. All rights reserved.