THE EPIDEMIOLOGY OF HEART-FAILURE - THE FRAMINGHAM-STUDY
THE EPIDEMIOLOGY OF HEART-FAILURE - THE FRAMINGHAM-STUDY
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DOI：
10.1016/0735-1097(93)90455-a
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发表时间：
1993-10-01
影响因子：
24
通讯作者：
LEVY, D
中科院分区：
文献类型：
--
作者：
HO, KKL;PINSKY, JL;LEVY, D
在过去的20年中，充血性心力衰竭已成为住院越来越常见的原因，显然是一个重大的健康问题。弗雷明汉心脏研究的数据表明，充血性心力衰竭的发病率随年龄增长而增加，且男性高于女性。高血压和冠心病是发病前最常见的两种情况。糖尿病和心电图左心室肥厚也与心力衰竭风险增加有关。20世纪80年代，年龄≥45岁人群中，充血性心力衰竭的年龄调整年发病率在男性为7.2例/1000人，女性为4.7例/1000人，而显性心力衰竭的年龄调整患病率在男性为24/1000人，女性为25/1000人。尽管缺血性心脏病和高血压的治疗有所改善，但在40年的观察期内，男性心力衰竭的年龄调整发病率每10年仅下降11%，女性每10年下降17%。此外，充血性心力衰竭仍然具有很高的致死率，男性中位生存时间为1.7年，女性为3.2年，男性5年生存率为25%，女性为38%。
Congestive heart failure has become an increasingly frequent reason for hospital admission during the last 2 decades and clearly represents a major health problem. Data from the Framingham Heart Study indicate that the incidence of congestive heart failure increases with age and is higher in men than in women. Hypertension and coronary heart disease are the two most common conditions predating its onset. Diabetes mellitus and electrocardiographic left ventricular hypertrophy are also associated with an increased risk of heart failure. During the 1980s, the annual age-adjusted incidence of congestive heart failure among persons aged greater than or equal to 45 years was 7.2 cases/1,000 in men and 4.7 cases/1,000 in women, whereas the age adjusted prevalence of overt heart failure was 24/1,000 in men and 25/1,000 in women. Despite improved treatments far ischemic heart disease and hypertension, the age-adjusted incidence of heart failure has declined by only 11%/calendar decade in men and by 17%/calendar decade in women during a 40-year period of observation. In addition, congestive heart failure remains highly lethal, with a median survival time of 1.7 gears in men and 3.2 years in women and a 5-year survival rate of 25% in men and 38% in women.