The influence of socioeconomic factors on the occurrence of fetal alcohol syndrome.

The influence of socioeconomic factors on the occurrence of fetal alcohol syndrome.
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社会经济因素对胎儿酒精综合征发生的影响。

DOI:
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发表时间:
1987
期刊:
Advances in Alcohol & Substance Abuse
影响因子:
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通讯作者:
D. Gromisch
D. Gromisch
中科院分区:
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文献类型:
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作者:
N. Bingol;C. Schuster;M. Fuchs;S. Iosub;Gudrun Turner;R. K. Stone;D. Gromisch

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本研究旨在比较中下层慢性酒精中毒母亲和中上层慢性酒精中毒母亲的子女Fas的表现,并将这些子女与非酒精对照组的子女进行比较。上、中、下层饮酒母亲的Fas发生率分别为4.5%和70.9%,差异有高度显著性(P<0.05)。中上层酗酒妇女出生时的平均体重、身长和头围为-ISD,而下层酗酒妇女的出生时平均体重、身长和头围为-2SD。所有其他参数,如先天畸形率、发育不良、智力发育迟缓,在下层酗酒妇女的子女中也显著更高(p<0.01)。在酗酒妇女的中上阶层子女中,有21%的人发现注意力缺陷障碍,而在较低社会经济群体的子女中,这一比例为71%(p<0.01)。
This study was designed to compare manifestations of FAS in the offspring of lower and upper middle class chronic alcoholic mothers, and to compare these offspring with those of nonalcoholic controls. There was highly significant difference in the incidence of FAS offspring between upper middle and lower class alcoholic mothers, 4.5% versus 70.9% respectively. Mean weight, length, and head circumference at birth in children of upper middle class alcoholic women was -ISD, those of lower class alcoholic women fell into -2SD. All other parameters, congenital malformation rate, failure to thrive, mental retardation were also significantly greater in children of lower class alcoholic women (p less than or equal to .01). Attention deficit disorder was found in 21% of upper middle class offspring of alcoholic women as compared to 71% in the children of the lower socioeconomic group (p less than or equal to .01).