Comparative outcomes among the problem areas of interpersonal psychotherapy for depression.
Comparative outcomes among the problem areas of interpersonal psychotherapy for depression.
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DOI：
10.1002/da.20661
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发表时间：
2010-05
影响因子：
7.4
通讯作者：
Fagiolini, A.
中科院分区：
文献类型：
--
作者：
Levenson, J. C.;Frank, E.;Cheng, Y.;Rucci, P.;Janney, C. A.;Houck, P.;Forgione, R. N.;Swartz, H. A.;Cyranowski, J. M.;Fagiolini, A.
虽然人际心理治疗（IPT）是一种有效的治疗急性抑郁症的方法，但在四个IPT问题领域（悲伤、角色转换、角色纠纷、人际缺陷）中治疗的相对疗效却很少受到关注。我们通过比较专注于每个问题领域的患者的治疗成功率来评估IPT的特异性。此外，我们试图了解与患者当前抑郁症发病最密切相关的患者特征和人际关系问题如何促成IPT的成功。符合DSM-IV重度抑郁症发作标准的患者（n=182）接受每周一次的IPT治疗。缓解被定义为抑郁症汉密尔顿评定量表17项平均得分在3周内达到或低于7分。使用DSM-IV人格障碍结构化临床访谈诊断人格障碍。与我们的预测相反，集中治疗人际关系缺陷的患者需要更长的时间才能缓解，生存分析表明，集中治疗四个问题领域的患者在缓解时间上没有差异。人际关系缺陷组的患者也不太可能有II轴诊断。在控制协变量后，专注于角色转换治疗的患者比专注于角色争议治疗的患者缓解得更快。通过熟练使用IPT策略和策略，并在适当的情况下进行仔细的药物管理，本研究中的患者的治疗重点是每个问题领域，由训练有素的IPT临床医生治疗，取得了同样的成功。
Although interpersonal psychotherapy (IPT) is an efficacious treatment for acute depression, the relative efficacy of treatment in each of the four IPT problem areas (grief, role transitions, role disputes, interpersonal deficits) has received little attention. We evaluated the specificity of IPT by comparing treatment success among patients whose psychotherapy focused on each problem area. Moreover, we sought to understand how the patient characteristics and interpersonal problems most closely linked to the onset of a patient’s current depression contributed to IPT success. Patients meeting DSM-IV criteria for an episode of major depressive disorder (n=182) were treated with weekly IPT. Remission was defined as an average Hamilton Rating Scale for Depression 17-item score of 7 or below over 3 weeks. Personality disorders were diagnosed using the Structured Clinical Interview for DSM-IV Personality Disorders. Contrary to our prediction that patients whose treatment was focused on interpersonal deficits would take longer to remit, survival analyses indicated that patients receiving treatment focused on each of the four problem areas did not differ in their times to remission. Nor were patients in the interpersonal deficits group more likely to have an Axis II diagnosis. Patients whose treatment focused on role transitions remitted faster than those whose treatment focused on role disputes, after controlling for covariates. With skillful use of IPT strategies and tactics and with careful medication management where appropriate, patients in this study whose treatment focused on each problem area were treated with equal success by trained IPT clinicians.
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影响因子：
2.3
作者：
Bearden, C;Lavelle, N;Frank, E
通讯作者：
Frank, E
影响因子：
11
作者：
HAMILTON, M
通讯作者：
HAMILTON, M
影响因子：
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作者：
Frank, Ellen;Cassano, Giovanni B.;Forgione, Rocco Nicola
通讯作者：
Forgione, Rocco Nicola
影响因子：
6.9
作者：
Cyranowski, JM;Frank, E;Kupfer, DJ
通讯作者：
Kupfer, DJ
影响因子：
1.9
作者：
Markowitz, JC;Bleiberg, KL;Levitan, E
通讯作者：
Levitan, E