Improved effects of a double suicide gene system on prostate cancer cells by targeted regulation of prostate‐specific membrane antigen promoter and enhancer
Improved effects of a double suicide gene system on prostate cancer cells by targeted regulation of prostate‐specific membrane antigen promoter and enhancer
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DOI：
10.1111/j.1442-2042.2008.02034.x
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发表时间：
2008-05
影响因子：
2.6
通讯作者：
P. Zhang;H. Zeng;Q. Wei;Yi-ping Lu;Xiang Li;Jia Wang;F. Zhao;Hong Li
中科院分区：
文献类型：
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作者：
P. Zhang;H. Zeng;Q. Wei;Yi-ping Lu;Xiang Li;Jia Wang;F. Zhao;Hong Li
目的：探讨由前列腺特异性膜抗原（PSMA）启动子和增强子控制的胞嘧啶脱氨酶（CD）和尿嘧啶磷酸核糖转移酶（UPRT）双表达质粒系统对前列腺癌细胞的特异性杀伤作用。
Objective: To explore the specific killing effect on prostate cancer cells of a dual cytosine deaminase (CD) and uracil phosphoribosyltransferase (UPRT) expression plasmid system controlled by the prostate‐specific membrane antigen (PSMA) promoter and enhancer.