Regional cerebral activity associated with the incidental processing of pseudo-words
Regional cerebral activity associated with the incidental processing of pseudo-words
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DOI：
10.1002/hbm.460030209
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发表时间：
1995-01-01
影响因子：
4.8
通讯作者：
Frackowiak, RSJ
中科院分区：
文献类型：
--
作者：
Frith, CD;Kapur, N;Frackowiak, RSJ
为了研究与“伴随性”认知加工相关的大脑活动，在六名志愿者监测一系列假词（例如，FLOPE）时测量了局部脑血流（rCBF），监测的是字母显示为蓝色而非白色的罕见情况。在对照条件下，重复呈现相同的假词。在一种实验条件下，所有60个假词都不同，而在另一种条件下有18次重复。尽管执行监测任务不需要“阅读”假词，但随后对这些刺激的强制选择再认记忆显著高于随机水平。此外，三种条件之间的血流存在显著差异。当呈现不同的假词时，与形状和物体识别相关的脑区（双侧纹外皮层）、与视觉词形相关的脑区（左侧颞下回）以及与发音词形相关的脑区（布洛卡区）的活动显著增强，尽管执行监测任务不需要关于假词的这些信息。在一些词重复的条件下，右侧舌回的活动显著减少。因此，该区域可能是言语刺激重复启动的一个可能的解剖学部位。这些结果表明在设计功能成像实验的任务时考虑伴随性加工的重要性。（C）1995威利 - 利斯公司
In order to study brain activity associated with ''incidental'' cognitive processing, regional cerebral blood now (rCBF) was measured in six volunteers while they monitored a sequence of pseudo-words (e.g., FLOPE) for the rare occasions when the letters were displayed in blue rather than white. In the control condition, the same pseudo-word was presented repeatedly. In one experimental condition all 60 pseudo-words were different, while in the other there were 18 repetitions. Although it was not necessary to ''read'' the pseudo-words to perform the monitoring task, subsequent forced choice recognition memory for these stimuli was significantly greater than chance. Furthermore, there were significant differences in blood flow between the three conditions. When different pseudo-words were presented there was significantly greater activity in brain areas concerned with shape and object identity (extrastriate cortex bilaterally), with visual word form (left inferior temporal gyrus), and with articulatory word form (Broca's area) even though none of this information about the pseudo-words was needed for performance of the monitoring task. In the condition in which some of the words were repeated, there was significantly reduced activity in the right lingual gyrus. This area may therefore be a possible anatomical locus for repetition priming with verbal stimuli. These results indicate the importance of taking into account incidental processing when designing tasks for functional imaging experiments. (C) 1995 Wiley-Liss, Inc.