Classification of visual field abnormalities in the Ocular Hypertension Treatment Study

Classification of visual field abnormalities in the Ocular Hypertension Treatment Study
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DOI:
10.1001/archopht.121.5.643
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发表时间:
2003-05-01
影响因子:
--
通讯作者:
Gordon, MO
Gordon, MO
中科院分区:
其他
文献类型:
--
作者:
Keltner, JL;Johnson, CA;Gordon, MO

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目的:(1)建立一个视野(VF)异常的分类系统,(2)确定阅片者间和重测一致性,(3)确定高眼压治疗研究中各种VF缺陷的频率。方法:每6个月进行一次随访VF,并监测异常情况,如青光眼半视野测试结果或校正模式SD超出正常范围。截至2002年1月1日,1636例患者有2509个异常VF。三名阅片师使用VF阅读中心开发的分类系统对每个半野进行独立分类。重读异常VF的一个子集(50%),以评估重测读片者的一致性。平均偏差分别计算的hemifields作为VF loss.Main结果的严重程度的指数:97% interreader hemifields agreements.Results:平均hemifields分类协议(任何2之间的3个读者)为5018 hemifields为97%和88%的1266异常VF重读(第一和第二分类之间的协议)。青光眼模式的损失(部分弓形,旁中央,鼻台阶缺陷)组成的VF defects.Conclusion:高眼压治疗研究分类系统具有较高的重现性,并提供了一个可能的命名为特征VF缺陷的大多数。
Objectives: (1) To develop a classification system for visual field (VF) abnormalities, (2) to determine interreader and test-retest agreement, and (3) to determine the frequency of various VF defects in the Ocular Hypertension Treatment Study.Methods: Follow-up VFs are performed every 6 months and are monitored for abnormality, indicated by a glaucoma hemifield test result or a corrected pattern SD outside the normal limits. As of January 1, 2002, 1636 patients had 2509 abnormal VFs. Three readers independently classified each hemifield using a classification system developed at the VF reading center. A subset (50%) of the abnormal VFs was reread to evaluate test-retest reader agreement. A mean deviation was calculated separately for the hemifields as an index to the severity of VF loss.Main Outcome Measures: A 97% interreader hemifield agreement.Results: The average hemifield classification agreement (between any 2 of 3 readers) for 5018 hemifields was 97% and 88% for the 1266 abnormal VFs that were reread (agreement between the first and second classifications). Glaucomatous patterns of loss (partial arcuate, paracentral, and nasal step defects) composed the majority of VF defects.Conclusion: The Ocular Hypertension Treatment Study classification system has high reproducibility and provides a possible nomenclature for characterizing VF defects.