Ag2CO3/CA-AA-AmidPhos Multifunctional Catalysis in the Enantioselective 1,3-Dipolar Cycloaddition of Azomethine Ylides.
Ag2CO3/CA-AA-AmidPhos Multifunctional Catalysis in the Enantioselective 1,3-Dipolar Cycloaddition of Azomethine Ylides.
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DOI：
10.1021/acs.orglett.5b03430
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发表时间：
2016-01
期刊：
影响因子：
5.2
通讯作者：
Haifei Wang;Qifu Deng;Zhi-Wen Zhou;Shunqin Hu;Zhi-guo Liu;Li-Yi Zhou
中科院分区：
文献类型：
--
作者：
Haifei Wang;Qifu Deng;Zhi-Wen Zhou;Shunqin Hu;Zhi-guo Liu;Li-Yi Zhou
新型Ag 2CO 3/CA-AA-amidphos配合物在偶氮甲碱叶立德的不对称1，3-偶极环加成反应中被证明是高效的多功能催化剂。在最佳条件下，以优异的产率（高达99%）和对映体选择性（高达96%ee）获得了高度官能化的内-4吡咯烷。
The new Ag2CO3/CA-AA-amidphos complexes have been demonstrated as highly efficient multifunctional catalysts in the asymmetric 1,3-dipolar cycloaddition of azomethine ylides. Under optimal conditions, highly functionalized endo-4 pyrrolidines were obtained with excellent yields (up to 99% yield) and enantioselectivities (up to 96% ee).