CIRCADIAN PHASE RESPONSE CURVES FOR DARK PULSES IN THE HAMSTER
CIRCADIAN PHASE RESPONSE CURVES FOR DARK PULSES IN THE HAMSTER
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DOI：
10.1007/bf00609437
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发表时间：
1982-01-01
期刊：
影响因子：
--
通讯作者：
RUSAK, B
中科院分区：
文献类型：
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作者：
BOULOS, Z;RUSAK, B
仓鼠保持在恒定的照明暴露于2或6小时的黑暗脉冲在其昼夜活动节律的各个阶段。当呈现在活动开始的时间附近时，脉冲导致相位提前，并且当呈现在日常活动结束时，它们导致相位延迟。另一些作者指出，在恒定的黑暗中，以相同相位呈现的光脉冲引起相反方向的相移，光脉冲和暗脉冲的相位响应曲线可能是镜像。暗脉冲引起的相位依赖性的变化，短暂的和持久的，在自由运行的节奏期间，和几个脉冲后立即分裂成2个组件的活动节奏。这种效应可以反映2个耦合振荡器对暗脉冲的差分响应。
Hamsters maintained under constant illumination were exposed to 2- or 6-h pulses of darkness at various phases of their circadian activity rhythms. When presented around the time of activity onset, the pulses resulted in phase advances, and when presented toward the end of daily activity, they resulted in phase delays. Other authors have shown that light pulses presented at the same phases in constant darkness cause phase shifts in the opposite directions, phase response curves for light and dark pulses are probably mirror images. Dark pulses caused phase-dependent changes, both transient and long-lasting, in the period of the free-running rhythms, and a few pulses were immediately followed by splitting of the activity rhythms into 2 components. Such effects may reflect a differential responsiveness of 2 coupled oscillators to dark pulses.