High and low hemoglobin glycation phenotypes in type 1 diabetes - A challenge for interpretation of glycemic control
High and low hemoglobin glycation phenotypes in type 1 diabetes - A challenge for interpretation of glycemic control
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DOI：
10.1016/s1056-8727(01)00227-6
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发表时间：
2002-09-01
影响因子：
3
通讯作者：
Chalew, SA
中科院分区：
文献类型：
--
作者：
Hempe, JM;Gomez, R;Chalew, SA
本研究检验了这样的假设：在先前血糖水平相似的个体中，糖化血红蛋白（HbA 1c）和平均血糖（MBG）水平之间的关系存在一致的个体差异。收集了128名1型糖尿病儿童和青少年长达2.3年的血糖数据。HbA1c值与MBG水平进行日期匹配，MBG水平是根据前30天内收集的85次自我监测血糖测量的平均值计算的。MBG与HbA1c呈直线相关（HbA1c = 0.027 × MBG +5.8，n = 682，r=.71，P
This study tested the hypothesis that there are consistent individual differences in the relationship between glycated hemoglobin (HbA1c) and mean blood glucose (MBG) levels in individuals with similar preceding blood glucose levels. Blood glucose data were collected for up to 2.3 years by 128 children and adolescents with type 1 diabetes. HbA1c values were date-matched with MBG levels calculated from an average of 85 self-monitored blood glucose measurements collected in the previous 30 days. There was significant linear correlation between MBG and HbA1c (HbA1c = 0.027 x MBG + 5.8, n = 682, r=.71, P