Acute exposure to blue wavelength light during memory consolidation improves verbal memory performance
Acute exposure to blue wavelength light during memory consolidation improves verbal memory performance
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DOI：
10.1371/journal.pone.0184884
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发表时间：
2017-09-18
期刊：
影响因子：
3.7
通讯作者：
Killgore, William D. S.
中科院分区：
文献类型：
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作者：
Alkozei, Anna;Smith, Ryan;Killgore, William D. S.
研究表明，急性暴露于蓝色波长内的光可以增强警觉性和警惕性，并提高反应时间任务的速度，这可能是由于去甲肾上腺素能系统的激活。然而，目前尚不清楚蓝光的影响是否超出了简单的警觉过程，也增强了认知的其他方面，如记忆表现。本研究的目的是调查在健康正常休息的个体中，在早晨在言语记忆巩固（即，1.5在记忆获得后24小时）使用简化版本的加州言语学习测试（CVLT-II）。在延迟回忆中，在巩固期接受蓝光（n = 12）的个体比接受琥珀色光照射（n = 18）的个体表现出更好的长延迟口头回忆，同时控制了一般智力，抑郁症状和习惯性觉醒时间的影响。这些发现扩展了先前的工作，证明了蓝光对大脑激活和警觉性的影响，以进一步证明其在促进更好的记忆巩固和随后的口头材料保留方面的有效性。虽然是初步的，但这些发现指出了蓝色波长光在优化健康人群记忆性能方面的潜在应用。蓝光照射是否也可以提高记忆缺陷临床人群的表现还有待确定。
Acute exposure to light within the blue wavelengths has been shown to enhance alertness and vigilance, and lead to improved speed on reaction time tasks, possibly due to activation of the noradrenergic system. It remains unclear, however, whether the effects of blue light extend beyond simple alertness processes to also enhance other aspects of cognition, such as memory performance. The aim of this study was to investigate the effects of a thirty minute pulse of blue light versus placebo (amber light) exposure in healthy normally rested individuals in the morning during verbal memory consolidation (i.e., 1.5 hours after memory acquisition) using an abbreviated version of the California Verbal Learning Test (CVLT-II). At delayed recall, individuals who received blue light (n = 12) during the consolidation period showed significantly better long-delay verbal recall than individuals who received amber light exposure (n = 18), while controlling for the effects of general intelligence, depressive symptoms and habitual wake time. These findings extend previous work demonstrating the effect of blue light on brain activation and alertness to further demonstrate its effectiveness at facilitating better memory consolidation and subsequent retention of verbal material. Although preliminary, these findings point to a potential application of blue wavelength light to optimize memory performance in healthy populations. It remains to be determined whether blue light exposure may also enhance performance in clinical populations with memory deficits.