STEREOTAXIC RADIOTHERAPY OF MALIGNANCIES IN THE ABDOMEN - METHODOLOGICAL ASPECTS
STEREOTAXIC RADIOTHERAPY OF MALIGNANCIES IN THE ABDOMEN - METHODOLOGICAL ASPECTS
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DOI：
10.3109/02841869409121782
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发表时间：
1994-01-01
期刊：
影响因子：
3.1
通讯作者：
SVANSTROM, R
中科院分区：
文献类型：
--
作者：
LAX, I;BLOMGREN, H;SVANSTROM, R
一种立体定向高剂量放射治疗腹部恶性肿瘤的方法已经开发出来。已经开发了用于身体的立体定向框架，并且描述了用于将患者固定在框架中的方法。对于90%的患者设置，肝脏和肺部肿瘤立体定向系统的再现性在5-8 mm范围内。通过对腹部施加压力，将腹部运动减少到5-10 mm。一种分析方法被用来计算在等中心治疗技术中连续束的剂量分布。异质靶剂量的优点被证明并提出用于本申请。提出了一种使用八个单独成形的光束的非共面治疗技术，并已用于患者治疗。图中显示了肝转移患者的剂量分布以及靶点和肝脏的剂量体积直方图。
A method for sterotactic high-dose radiotherapy of malignancies in the abdomen has been developed. A stereotactic frame for the body has been developed and a method for fixation of the patient in the frame is described. The reproducibility in the stereotactic system of tumours in the liver and the lung was found to be within 5-8 mm for 90% of the patient set-ups. The diaphragmatic movements were reduced to 5-10 mm, by applying a pressure on the abdomen. An analytical method is used to calculate dose distributions for a continuum of beams in an isocentric treatment technique. The advantage of a heterogeneous target dose is demonstrated and proposed for the present application. A non-coplanar treatment technique, using eight individually shaped beams is proposed and has been used for patient treatments. The dose distribution for a patient with a metastasis in the liver is shown as well as dose volume histograms for the target and the liver.