Severe hemolytic anemia and acute renal failure after mitral valve repair associated with non-endothelialization of artificial chordae tendinae: case report.
Severe hemolytic anemia and acute renal failure after mitral valve repair associated with non-endothelialization of artificial chordae tendinae: case report.
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二尖瓣修复术后与人工腱索非内皮化相关的严重溶血性贫血和急性肾功能衰竭：病例报告
DOI：
10.1186/s13019-021-01686-6
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发表时间：
2021-10-16
影响因子：
1.6
通讯作者：
Duan QJ
中科院分区：
文献类型：
--
作者：
Li J;Duan QJ
背景机械性溶血性贫血和急性肾功能衰竭是二尖瓣修复术的罕见并发症。病例介绍我们报告一例使用人工腱索二尖瓣修复术后发生严重溶血性贫血和严重急性肾功能衰竭的独特病例。包括血浆置换和输血在内的保守治疗无效。机械性溶血的主要原因是源自瓣膜中心并撞击瓣膜成形环的轻度二尖瓣返流。二尖瓣置换术后，溶血性贫血逐渐消退。新的人工腱索在手术中被发现完全没有内皮化。非内皮化的人工腱索也可能发挥作用，在机械性anemia.ConclusionsThe机械性溶血的成因是轻微的二尖瓣返流，从中心的阀门和打击瓣环成形环。异物的非内皮化可能是二尖瓣修复后溶血的另一机制。
BackgroundMechanical hemolytic anemia and acute renal failure are rare complications of mitral valve repair.Case presentationWe report a unique case of severe hemolytic anemia and severe acute renal failure after mitral valve repair using artificial chordae tendinae. Conservative therapy including plasmapheresis and blood transfusion was not effective. The major cause of the mechanical hemolysis was mild mitral regurgitation originating from the centre of the valve and striking the annuloplasty ring. The hemolytic anemia resolved gradually after the replacement of mitral valve. The new artificial chordae tendinae was found to be completely non-endothelialized in the surgery. Non-endothelialization of artificial chordae tendinae may also play a role in the genesis of mechanical anemia.ConclusionsThe major cause of the mechanical hemolysis was mild mitral regurgitation originating from the centre of the valve and striking the annuloplasty ring. Non-endothelialization of foreign materials might be another mechanism of hemolysis after mitral repair.
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影响因子：
1.8
作者：
Cardoso C;Cachado P;Garcia T
通讯作者：
Garcia T
DOI：
10.1016/0735-1097(95)00403-3
发表时间：
1996-02-01
影响因子：
24
作者：
Garcia, MJ;Vandervoort, P;Griffin, BP
通讯作者：
Griffin, BP
影响因子：
13.2
作者：
Concepcion, Beatrice;Korbet, Stephen M.;Schwartz, Melvin M.
通讯作者：
Schwartz, Melvin M.
影响因子：
1.5
作者：
MAURER, I;BERNHARD, A
通讯作者：
BERNHARD, A
影响因子：
4.6
作者：
Lam, BK;Cosgrove, DM;Gillinov, AM
通讯作者：
Gillinov, AM