Laser immunotherapy - A novel treatment modality for metastatic tumors

Laser immunotherapy - A novel treatment modality for metastatic tumors
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DOI:
10.1385/mb:25:1:37
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发表时间:
2003-09-01
影响因子:
2.6
通讯作者:
Nordquist, RE
Nordquist, RE
中科院分区:
医学4区
文献类型:
--
作者:
Chen, WR;Carubelli, R;Nordquist, RE

文献摘要

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激光免疫治疗是一种治疗转移性肿瘤的新方法。它结合了选择性光热激光组织相互作用直接肿瘤破坏和免疫佐剂定向模拟免疫反应。在使用大鼠转移性肿瘤模型的实验中,激光免疫治疗可以根除已治疗的原发肿瘤和未治疗的远处转移瘤。它还能诱导抗肿瘤抵抗。
Laser immunotherapy is a novel approach for the treatment of metastatic tumors. It combines a selective photothermal laser-tissue interaction for direct tumor destruction and an immunoadjuvant-directed simulation for immune responses. In experiments using a rat metastatic tumor model, laser immunotherapy resulted in the eradication of-both, treated primary tumors and untreated metastases at remote sites. It also induced anti-tumor resistance.