A new methodology for multiscale myocardial deformation and strain analysis based on tagging MRI.
A new methodology for multiscale myocardial deformation and strain analysis based on tagging MRI.
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DOI:
10.1155/2010/341242
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发表时间:
2010
影响因子:
7.6
通讯作者:
van Assen H
中科院分区:
文献类型:
--
作者:
Florack L;van Assen H
Myocardial deformation and strain can be investigated using suitably encoded cine MRI that admits disambiguation of material motion. Practical limitations currently restrict the analysis to in-plane motion in cross-sections of the heart (2D + time), but the proposed method readily generalizes to 3D + time. We propose a new, promising methodology, which departs from a multiscale algorithm that exploits local scale selection so as to obtain a robust estimate for the velocity gradient tensor field. Time evolution of the deformation tensor is governed by a first-order ordinary differential equation, which is completely determined by this velocity gradient tensor field. We solve this matrix-ODE analytically and present results obtained from healthy volunteers as well as from patient data. The proposed method requires only off-the-shelf algorithms and is readily applicable to planar or volumetric tagging MRI sampled on arbitrary coordinate grids.