A new methodology for multiscale myocardial deformation and strain analysis based on tagging MRI.

A new methodology for multiscale myocardial deformation and strain analysis based on tagging MRI.
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DOI:
10.1155/2010/341242
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发表时间:
2010
影响因子:
7.6
通讯作者:
van Assen H
van Assen H
中科院分区:
其他
文献类型:
--
作者:
Florack L;van Assen H

文献摘要

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心肌变形和应变可以使用适当编码的电影MRI进行研究,它允许消除材料运动的歧义。目前的实际局限性限制了对心脏横截面(2D +时间)中平面内运动的分析,但所提出的方法很容易推广到3D +时间。我们提出了一种新的、有前途的方法,该方法与利用局部尺度选择的多尺度算法不同,以便获得速度梯度张量场的鲁棒估计。变形张量的时间演化是由一阶常微分方程,这是完全由这个速度梯度张量场。我们解决这个矩阵ODE分析和健康志愿者以及从患者数据中获得的结果。所提出的方法只需要现成的算法,是很容易适用于平面或体积标记MRI采样任意坐标网格。
Myocardial deformation and strain can be investigated using suitably encoded cine MRI that admits disambiguation of material motion. Practical limitations currently restrict the analysis to in-plane motion in cross-sections of the heart (2D + time), but the proposed method readily generalizes to 3D + time. We propose a new, promising methodology, which departs from a multiscale algorithm that exploits local scale selection so as to obtain a robust estimate for the velocity gradient tensor field. Time evolution of the deformation tensor is governed by a first-order ordinary differential equation, which is completely determined by this velocity gradient tensor field. We solve this matrix-ODE analytically and present results obtained from healthy volunteers as well as from patient data. The proposed method requires only off-the-shelf algorithms and is readily applicable to planar or volumetric tagging MRI sampled on arbitrary coordinate grids.