Eliminating onchocerciasis after 14 years of vector control:: A proved strategy
Eliminating onchocerciasis after 14 years of vector control:: A proved strategy
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DOI：
10.1086/322789
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发表时间：
2001-08-15
影响因子：
6.4
通讯作者：
Boatin, BA
中科院分区：
文献类型：
--
作者：
Hougard, JM;Alley, ES;Boatin, BA
从1976年到1989年，在盘尾丝虫病高度流行的西非大片稀树草原地区（面积约700，000 km（2））的河流沿线，沿着进行每周一次的空中喷洒作业，防治黑蝇。在病媒控制4年后，地方病流行程度开始显著下降，1989年变得很低。在没有开展任何病媒控制活动或化疗的情况下，这一情况得以维持，也没有发现任何新病例。2000年进行的一项眼科研究证实了这些良好的结果，在接受检查的人群中仅显示了瘢痕性眼部病变。这些结果导致的结论是，14年的病媒控制可以实现长期消除盘尾丝虫病，即使在没有化疗的情况下，只要治疗地区没有受到感染的人或苍蝇携带的外源寄生虫的任何污染。
From 1976 through 1989, weekly aerial spraying operations against blackflies were carried out along the rivers of a wide savanna area of West Africa (similar to 700,000 km(2)) where onchocerciasis was hyperendemic. The level of endemicity began to decrease significantly after 4 years of vector control and became very low in 1989. This situation has been maintained without any vector control activity or chemotherapy, and no incidence of any new cases has been detected. An ophthalmological study carried out in 2000 has confirmed these good results, showing only cicatricial ocular lesions in the examined population. These results led to the conclusion that 14 years of vector control may achieve long-term elimination of onchocerciasis, even in the absence of chemotherapy, provided that the treated areas are not subjected to any contamination by exogenous parasites carried in infected humans or flies.