The roles of histone acetylation in seed performance and plant development.
The roles of histone acetylation in seed performance and plant development.
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DOI：
10.1016/j.plaphy.2014.09.010
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发表时间：
2014-11
期刊：
影响因子：
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通讯作者：
Zhi Wang;H. Cao;Fengying Chen;Yong-xiu Liu
中科院分区：
文献类型：
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作者：
Zhi Wang;H. Cao;Fengying Chen;Yong-xiu Liu
组蛋白乙酰化通过染色质修饰调节基因转录，在植物发育和对环境信号的响应中起着至关重要的作用。组蛋白乙酰转移酶（histone acetyltransferases, HATs）和组蛋白去乙酰化酶（histone deacetylases, hdac）在植物不同组织和发育阶段控制着组蛋白乙酰化的稳态。从模式植物拟南芥中获得了hat（如GCN5）和hdac（如HDA19、HDA6）的功能及其辅助因子的丰富知识。但是，了解其他HATs和hdac的个别作用需要更多的工作，特别是在水稻、玉米和小麦等主要粮食作物方面。最近已经发现许多共同调节因子在某些特定的发育过程中作为HAT或HDAC复合物的组成部分起作用。这些发现揭示了一个独特而有趣的表观遗传调控网络，它由hat、hdac和协同调控因子组成，在种子性能、开花时间、植物形态发生、植物对胁迫的反应等方面发挥着重要作用。本文对组蛋白乙酰化的研究进展进行了综述，并提出了组蛋白乙酰化的研究方向，以期为我们理解植物发育的表观遗传密码，提高作物产量和品质提供一个新的窗口。
Histone acetylation regulates gene transcription by chromatin modifications and plays a crucial role in the plant development and response to environment cues. The homeostasis of histone acetylation is controlled by histone acetyltransferases (HATs) and histone deacetylases (HDACs) in different plant tissues and development stages. The vigorous knowledge of the function and co-factors about HATs (e.g. GCN5) and HDACs (e.g. HDA19, HDA6) has been obtained from model plant Arabidopsis. However, understanding individual role of other HATs and HDACs require more work, especially in the major food crops such as rice, maize and wheat. Many co-regulators have been recently identified to function as a component of HAT or HDAC complex in some specific developmental processes. The described findings show a distinctive and interesting epigenetic regulation network composed of HATs, HDACs and co-regulators playing crucial roles in the seed performance, flowering time, plant morphogenesis, plant response to stresses etc. In this review, we summarized the recent progresses and suggested the perspective of histone acetylation research, which might provide us a new window to understand the epigenetic code of plant development and to improve the crop production and quality.