Dynamics of O2, CO2, lactate, and acid exchange during contractions and recovery.
Dynamics of O2, CO2, lactate, and acid exchange during contractions and recovery.
复制标题
收缩和恢复期间氧气、二氧化碳、乳酸和酸交换的动态。
DOI：
10.1152/jappl.1983.54.6.1687
复制
发表时间：
1983
期刊：
影响因子：
--
通讯作者：
Chirtel,SJ
中科院分区：
文献类型：
--
作者：
Barbee,RW;Stainsby,WN;Chirtel,SJ
方法用戊巴比妥钠（30 mg/kg，静脉注射）麻醉 8 只体重在 12 至 18 kg 之间的雌雄杂种狗。他们连接到一个呼吸器，该呼吸器经过调整以将呼出气体的呼气末二氧化碳浓度维持在 5 至 0.5%。需要时给予额外的麻醉剂。用肝素 (2,000-3,000 U/kg) 预防血液凝固。使用加热垫和辐射热测量食道温度并保持在 37℃ t 0.2。右股动脉插管以监测动脉血压并获取动脉血样本。研究的肌肉是左后腿的腓肠肌-跖肌组。它通过从大腿中部到脚踝的内侧切口暴露。将上面的肌肉双重结扎，并在系带之间切断。通过结扎除肌肉群之外的所有与腘静脉的血管连接以及通过结扎来自肌肉的不直接排入腘静脉的少数静脉，来隔离来自肌肉的静脉流出。腘静脉插管，静脉血通过硅橡胶管通过 3 毫米插管型电磁流量计引导，并通过左颈静脉返回动物。在每次实验期间，通过定时收集静脉流出物来校准流量计。将 PE-90 聚乙烯管穿过静脉血管管壁并穿入腘静脉中的插管尖端。另一端有一个 Y 连接到两个
METHODSEight mongrel dogs of both sexes weighing between 12 and 18 kg were anesthetized with pentobarbital sodium (30 mg/kg, iv). They were connected to a respirator that was adjusted to maintain the end-tidal CO2 of expired gas at 5 t 0.5%. Additional anesthetic was given when needed. Blood coagulation was prevented with heparin (2,000-3,000 U/kg). Esophageal temperature was measured and kept at 37OC t 0.2 by using a heating pad and radiant heat. The right femoral artery was cannulated to monitor arterial blood pressure and to obtain samples of arterial blood.The muscle studied was the gastrocnemius-plantaris group of the left hindleg. It was exposed via a medial incision from midthigh to ankle. The overlying muscles were doubly ligated, and cut between the ties. The venous outflow from the muscle was isolated by ligating all vascular connections to the popliteal vein except those from the muscle group and by ligating the few veins from the muscle that did not drain directly into the popliteal vein. The popliteal vein was cannulated and the venous blood conducted via Silastic tubing through a 3-mm cannulating-type electromagnetic flowmeter and back to the animal via the left jugular vein. The flowmeter was calibrated by timed collections of the venous effluent at intervals during each experiment. A PE-90 polyethylene tube was passed through the wall of the venous blood tubing and threaded to the tip of the cannula in the popliteal vein. The other end had a Y connection to two
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影响因子：
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DOI：
10.1093/ajcn/39.1.114
发表时间：
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期刊：
The American journal of clinical nutrition
影响因子：
--
作者：
Farris,RP;Cresanta,JL;Frank,GC;Webber,LS;Berenson,GS
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DOI：
10.1001/archpedi.1984.02140420045016
发表时间：
1984
期刊：
American journal of diseases of children (1960)
影响因子：
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作者：
Cresanta,JL;Srinivasan,SR;Webber,LS;Berenson,GS
通讯作者：
Berenson,GS