Relation of childhood height to obesity among adults: The Bogalusa Heart Study
Relation of childhood height to obesity among adults: The Bogalusa Heart Study
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DOI：
10.1542/peds.109.2.e23
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发表时间：
2002-02-01
期刊：
影响因子：
8
通讯作者：
Berenson, GS
中科院分区：
文献类型：
--
作者：
Freedman, DS;Khan, LK;Berenson, GS
目标。在之前的一项关于成人肥胖各种预测因素作用的研究中，我们发现相对较高的儿童在成年早期具有较高的体重指数（BMI; kg/m(2)）。在这项研究中，目的是确定儿童身高是否与成人肥胖有关，以及这种联系是否独立于儿童体重指数水平和三头肌皮肤厚度。儿童时期身高与成年期相对体重和皮肤褶（肩胛骨下和肱三头肌的总和）厚度的纵向关系在一个更大的样本（N = 1055）中进行了检验，这些样本是2至8岁的儿童，平均随访了18年。与身高低于性别和年龄特定中位数的儿童相比，年龄身高高于第95百分位(P)的儿童成年后BMI大于或等于30 kg/m(2)的可能性约为2.5倍，皮褶总数为90分之P的可能性约为5倍。虽然身高和肥胖在儿童中是相关的（r = 0.29），但在控制了儿童时期BMI和三头肌皮褶厚度后，观察到的纵向关系仍然存在。例如，在体重指数相同的儿童中，身高每差10厘米，成年后体重指数就会差0.9 kg/m(2)，皮褶量就会差4 mm。虽然这些结果需要在其他研究中得到证实，但儿童身高的信息有可能被用来更准确地识别那些在以后的生活中可能肥胖的儿童。
Objective. In a previous study of the role of various predictors of adult obesity, we found that relatively tall children had a higher body mass index (BMI; kg/m(2)) in early adulthood. In this study, the objective was to determine whether childhood height is related to adult adiposity and whether the association is independent of childhood levels of BMI and triceps skin-fold thickness.Methods. The longitudinal relations of childhood height to relative weight and skin-fold (sum of subscapular and triceps) thicknesses in adulthood were examined in a larger sample (N = 1055) of 2- to 8-year-olds who were followed for an average of 18 years.Results. Compared with children whose heights were below the gender- and age-specific median, a child with a height-for-age above the 95th percentile (P) was approximately 2.5 times as likely to have a BMI greater than or equal to 30 kg/m(2) and approximately 5 times as likely to have a skinfold sum >90th P in adulthood. Although height and adiposity were associated (r = 0.29) among children, the observed longitudinal relations persisted after controlling for BMI and the triceps skinfold thickness in childhood. For example, among children with the same BMI, each 10-cm difference in height was associated with differences in adulthood of 0.9 kg/m(2) for BMI and 4 mm for the skinfold sum.Conclusions. Although these results need to be confirmed in other studies, it is possible that information on childhood height could be used to identify more accurately children who are likely to be obese in later life.