Electrochemical quantification of some water soluble vitamins in commercial multi-vitamin using poly-amino acid caped by graphene quantum dots nanocomposite as dual signal amplification elements.
Electrochemical quantification of some water soluble vitamins in commercial multi-vitamin using poly-amino acid caped by graphene quantum dots nanocomposite as dual signal amplification elements.
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DOI：
10.1016/j.ab.2017.10.011
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发表时间：
2017-12
影响因子：
2.9
通讯作者：
Nasrin Shadjou;M. Hasanzadeh;A. Omari
中科院分区：
文献类型：
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作者：
Nasrin Shadjou;M. Hasanzadeh;A. Omari
商业多种维生素中的一些水溶性维生素(维生素B2、B9和C)的快速分析可以在分析实验室进行常规操作。本文报道了一种低毒、生物相容的聚合物“聚天冬氨酸-石墨烯量子点”的电聚合，作为一种新的策略对玻碳电极进行表面修饰，并制备了一种用于商业多种维生素中选定维生素测定的新界面。电化学沉积作为一种控制良好的合成过程，随后在−1.5~2 V范围内，采用循环伏安技术在聚天冬氨酸上逐层制备了石墨烯量子点纳米结构。场发射扫描电子显微镜显示石墨烯量子点被固定在聚天冬氨酸薄膜上。用循环伏安法、计时电流法和差示脉冲伏安法对修饰电极进行了测定，结果表明该修饰电极具有良好的电活性。峰电流的增强归因于聚天冬氨酸作为半导体聚合物的优异性能、石墨烯量子点作为高密度的边缘平面位置和化学修饰之间的协同耦合所产生的快速非均相电子转移动力学。在优化的分析条件下，所制备的传感器对维生素B_2、维生素B_9和维生素C的检测下限分别为0.22、0.1、0.1gμM。
Rapid analyses of some water soluble vitamins (Vitamin B2, B9, and C) in commercial multi vitamins could be routinely performed in analytical laboratories. This study reports on the electropolymerization of a low toxic and biocompatible polymer “poly aspartic acid-graphene quantum dots” as a novel strategy for surface modification of glassy carbon electrode and preparation a new interface for measurement of selected vitamins in commercial multi vitamins. Electrochemical deposition, as a well-controlled synthesis procedure, has been used for subsequently layer-by-layer preparation of graphene quantum dots nanostructures on a poly aspartic acid using cyclic voltammetry techniques in the regime of −1.5 to 2 V. The field emission scanning electron microscopy indicated immobilization of graphene quantum dots onto poly aspartic acid film. The modified electrode possessed as an effective electroactivity for detection of water soluble vitamins by using cyclic voltammetry, chronoamperometry and differential pulse voltammetry. Enhancement of peak currents is ascribed to the fast heterogeneous electron transfer kinetics that arise from the synergistic coupling between the excellent properties of poly aspartic acid as semiconducting polymer, graphene quantum dots as high density of edge plane sites and chemical modification. Under the optimized analysis conditions, the prepared sensor for detection of VB2, VB9, and VC showed a low limit of quantification 0.22, 0.1, 0.1 μM, respectively.