Effect of shift work on body mass index: results of a study performed in 319 glucose-tolerant men working in a Southern Italian industry
Effect of shift work on body mass index: results of a study performed in 319 glucose-tolerant men working in a Southern Italian industry
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DOI：
10.1038/sj.ijo.0802419
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发表时间：
2003-11-01
影响因子：
4.9
通讯作者：
Soleo, L
中科院分区：
文献类型：
--
作者：
Di Lorenzo, L;De Pergola, G;Soleo, L
目的：研究轮班工作对意大利南部普利亚某工业基地工作人员代谢和心血管危险因素的影响。设计：意大利南部某化工企业葡萄糖耐受工人轮班工作代谢影响的横断面研究。研究对象：受试者包括319名年龄在35 - 60岁之间的糖耐量男性个体。测量方法：人体测量参数（体重指数（BMI）和腰臀比（WHR）），空腹葡萄糖、胰岛素和脂质（总胆固醇、高密度脂蛋白胆固醇、甘油三酯）浓度，75 g-口服糖耐量试验（S-OGTT）期间的葡萄糖水平和收缩压和舒张压（分别为收缩压和舒张压）。结果：与日工相比，轮班工人的肥胖患病率更高，而体脂分布在两组之间没有差异。倒班工人的BMI高于白班工人，并且倒班工作与BMI相关，与年龄和工作时间无关。轮班工人的收缩压水平明显较高，这是由BMI独立影响的，而不是由轮班工作影响的，因此表明收缩压的差异很可能是由体脂增加介导的。结论：在意大利南部某工业基地的工人中，轮班工作可能直接导致体脂增加，并与较高的血压水平和代谢综合征的某些特征间接相关。
OBJECTIVE: To examine the influence of shift work on metabolic and cardiovascular risk factors in subjects working in an industry sited in Apulia, Southern Italy.DESIGN: Cross-sectional study of metabolic effects of shift work in glucose tolerant workers in a chemical industry in southern Italy.SUBJECTS: The subjects included 319 glucose tolerant male individuals, aged 35 - 60 y.MEASUREMENTS: Anthropometric parameters ( body mass index (BMI) and waist-to-hip ratio (WHR)), fasting concentrations of glucose, insulin, and lipids ( total cholesterol, HDL-cholesterol, triglycerides), the sum of glucose levels during 75 g-oral glucose tolerance test (S-OGTT), and systolic and diastolic blood pressure (SBP and DBP, respectively).RESULTS: The prevalence of obesity was higher among shift workers compared to day workers, whereas body fat distribution was not different between the two groups. Shift workers had higher BMI than day workers, and shift working was associated with BMI, independently of age and work duration. Shift workers had significantly higher SBP levels, which were independently influenced by BMI, but not by shift work, thus suggesting that the difference in SBP may well be mediated by the increased body fatness.CONCLUSION: In workers of an industry sited in Southern Italy, shift work may be directly responsible for increased body fatness and is indirectly associated with higher blood pressure levels and some features of metabolic syndrome.