THE UHF AND MICROWAVE DIELECTRIC-PROPERTIES OF NORMAL AND TUMOR-TISSUES - VARIATION IN DIELECTRIC-PROPERTIES WITH TISSUE WATER-CONTENT
THE UHF AND MICROWAVE DIELECTRIC-PROPERTIES OF NORMAL AND TUMOR-TISSUES - VARIATION IN DIELECTRIC-PROPERTIES WITH TISSUE WATER-CONTENT
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DOI：
10.1088/0031-9155/25/6/012
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发表时间：
1980-01-01
影响因子：
3.5
通讯作者：
FOSTER, KR
中科院分区：
文献类型：
--
作者：
SCHEPPS, JL;FOSTER, KR
在0.01~17 GHz的体温范围内，对狗的各种软组织和正常组织进行了介电测量。在1-5 GHz以上的微波频率下，组织的介电性质可以用与37度纯水相同的弛豫频率(25 GHz)来拟合德拜方程。C.组织的介电特性与其水分含量有很好的相关性。在0.1 GHz处，组织的电导率(接近细胞质本身的电导率)随着组织中水的体积分数而增加，这与以前在电解质溶液中观察到的蛋白质的情况一致。在低于1 GHz的频率下，组织水对组织介电常数的贡献由不同于描述电导率数据的水分的函数来拟合。建议了可用于预测该宽频率范围内其他软组织的介电特性的经验公式。[应用微波能量可以产生癌症热疗所需的受控局部热疗。]。
Dielectric measurements were made on various [dog] soft tumor and normal tissues between 0.01 and 17 GHz at body temperature. At microwave frequencies above 1-5 GHz, the tissue dielectric properties can be fitted to Debye equations with the same relaxation frequency (25 GHz) as found for pure water at 37.degree. C. The tissue dielectric properties correlate well with their water contents. The conductivity of the tissue at 0.1 GHz (which is close to that of the cytoplasm itself) increases with the volume fraction of water in the tissue, in a manner consistent with that previously observed in proteins suspended in electrolyte solution. The contribution of the tissue water to the tissue dielectric permittivity at frequencies below 1 GHz is fitted by a function of water content different to that describing the conductivity data. Empirical equations that may be used to predict the dielectric properties of other soft tissues within this wide frequency range are suggested. [Application of microwave energy can be used to produce the required controlled local hyperthermia necessary for the thermotherapy of cancer.].