Fluoxetine treatment of obsessive-compulsive disorder.
Fluoxetine treatment of obsessive-compulsive disorder.
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氟西汀治疗强迫症。
DOI：
10.1097/00004714-198508000-00003
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发表时间：
1985
影响因子：
2.9
通讯作者：
J. Himmelhoch
中科院分区：
文献类型：
--
作者：
S. Turner;R. Jacob;D. Beidel;J. Himmelhoch
采用单盲安慰剂设计，对10例强迫症患者服用新型抗抑郁药盐酸氟西汀进行疗效观察。从抑郁症、强迫症和强迫症本身方面检查氟西汀的作用。结果表明，氟西汀影响抑郁症状，但也有影响自我报告的措施，强迫症和仪式行为。结果进行了讨论，在强迫症的改善，改善抑郁症的初始水平的关系，和患者的耐受药物的能力。
Fluoxetine hydrochloride, a new antidepressant, was administered to 10 obsessive-compulsive patients, and the effects of treatment were examined in a single-blind placebo design. The effects of fluoxetine were examined with respect to depressive symptomatology and obsessions and compulsions per se. The results suggest that fluoxetine affected depressive symptoms but also had an effect on self-reported measures of obsessions and ritualistic behavior. Results are discussed in terms of improvement in obsessive-compulsive disorder, the relation of improvement to initial levels of depression, and patients' ability to tolerate the drug.