Cardiac Recovery During Long-Term Left Ventricular Assist Device Support
Cardiac Recovery During Long-Term Left Ventricular Assist Device Support
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DOI：
10.1016/j.jacc.2016.07.743
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发表时间：
2016-10-04
影响因子：
24
通讯作者：
Selzman, Craig H.
中科院分区：
文献类型：
--
作者：
Wever-Pinzon, Omar;Drakos, Stavros G.;Selzman, Craig H.
背景：开展左心室辅助装置（LVAD）研究项目的中心数量非常少。因此，这种现象已被报道在现实世界中的多中心注册作为一个罕见的events. AccurativesThis研究评估了心脏恢复与先验LVAD植入策略的桥梁恢复（BTR）的发病率，并构建了一个恢复predictive model.METHODS该研究包括LVAD收件人登记在机构间注册的机械辅助循环支持（INTERMACS）。在BTR和非BTR患者中评价心脏恢复。在犹他州心脏恢复（UCAR）项目的患者中，加权评分得到了推导和外部验证。结果在15，138例INTERMACS患者中，192例（1.3%）发生心脏恢复。BTR患者的恢复率为11.2%（n - 14），而非BTR患者为1.2%（n - 178）（p < 0.0001）。恢复的独立预测因素包括：年龄
BACKGROUND The number of centers with left ventricular assist device (LVAD) research programs focused on cardiac recovery is very small. Therefore, this phenomenon has been reported in real-world multi-center registries as a rare event.OBJECTIVES This study evaluated the incidence of cardiac recovery with an a priori LVAD implantation strategy of bridge-to-recovery (BTR) and constructed a recovery predictive model.METHODS The study included LVAD recipients registered in the Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS). Cardiac recovery was evaluated in BTR and non-BTR patients. A weighted score was derived and externally validated in patients of the Utah Cardiac Recovery (UCAR) program.RESULTS Of 15,138 INTERMACS patients, cardiac recovery occurred in 192 (1.3%). The incidence of recovery was 11.2% (n - 14) in BTR compared with 1.2% (n - 178) in non-BTR patients (p < 0.0001). Independent predictors of recovery included: age