Elastodynamics and arterial wall stress
Elastodynamics and arterial wall stress
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DOI：
10.1114/1.1467676
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发表时间：
2002-04-01
影响因子：
3.8
通讯作者：
Na, S
中科院分区：
文献类型：
--
作者：
Humphrey, JD;Na, S
分子和细胞生物学的最新进展强调了机械因素在调节血管系统中细胞和细胞外基质的结构和功能中的根本重要性。因此，精确计算动脉壁中的应力和应变场以及它们如何随着疾病、损伤和临床治疗而变化的动机越来越大。虽然有大量关于动脉力学的文献，但我们的理解还远未完成。在本文中，我们回顾了一些显着的结果，关于壁的属性，提出了一些可能的改进，在壁应力的计算，并确定了一些未解决的问题，为进一步的研究。(C)2002生物医学工程学会。
Recent advances in molecular and cell biology have emphasized the fundamental importance of mechanical factors in regulating the structure and function of cells and extracellular matrix in the vasculature. Consequently, there is an ever-greater motivation to calculate accurately the stress and strain fields in the arterial wall and how they change with disease, injury, and clinical treatment. Although there is an extensive literature on arterial mechanics, our understanding is still far from complete. In this paper, we review some of the salient findings with regard to wall properties, suggest some possible improvements in the calculation of wall stress, and identify some unresolved problems for further research. (C) 2002 Biomedical Engineering Society.