Medial prefrontal cortex generates frontal midline theta rhythm

Medial prefrontal cortex generates frontal midline theta rhythm
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DOI:
10.1097/00001756-199903170-00003
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发表时间:
1999-03-17
期刊:
影响因子:
1.7
通讯作者:
Takeda, M
Takeda, M
中科院分区:
医学4区
文献类型:
--
作者:
Ishii, R;Shinosaki, K;Takeda, M

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额中线theta节律(Fm Theta)是大脑额叶中线区域的一种独特的theta活动,在正常受试者集中执行心理任务时出现,反映了集中的注意加工。为了层析可视化地显示Fm theta的源电流密度分布,我们用4名健康受试者的通道全磁珠脑磁图系统记录了Fm theta,并应用了一种新的分析方法--合成孔径磁测法--自适应波束形成方法。在双侧额叶的脑磁图信号中可观察到fm theta。SAM分析显示,双侧前额叶内侧皮质,包括前扣带回皮质,是FM theta的来源。这一结果表明,注意力集中主要与内侧前额叶皮质有关。《神经报告》10:675-679(C)1999,Lippincott Williams&Wilkins.
FRONTAL midline theta rhythm (Fm theta) is a distinct theta activity of EEG in the frontal midline area that appears during concentrated performance of mental tasks in normal subjects and reflects focused attentional processing. To tomographically visualize the source current density distributions of Fm theta, we recorded Fm theta by using a 64-channel whole-bead MEG system from four healthy subjects, and applied a new analysis method, synthetic aperture magnetometry (SAM), an adaptive beam forming method. Fm theta was observed in the MEG signals over the bilateral frontal regions. SAM analysis showed bilateral medial prefrontal cortices, including anterior cingulate cortex, as the source of Fm theta. This result suggests that focused attention is mainly related to medial prefrontal cortex. NeuroReport 10:675-679 (C) 1999 Lippincott Williams & Wilkins.