PROVEAN web server: a tool to predict the functional effect of amino acid substitutions and indels

PROVEAN web server: a tool to predict the functional effect of amino acid substitutions and indels
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DOI:
10.1093/bioinformatics/btv195
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发表时间:
2015-08-15
期刊:
影响因子:
5.8
通讯作者:
Chan, Agnes P.
Chan, Agnes P.
中科院分区:
生物学3区
文献类型:
--
作者:
Choi, Yongwook;Chan, Agnes P.

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我们提出了一个web服务器来预测单个或多个氨基酸取代,插入和删除的功能影响,使用预测工具provan。该服务器提供来自任何生物体的蛋白质变异的快速分析,并且还支持在基因组和蛋白质水平上对人类和小鼠变异进行高通量分析。
We present a web server to predict the functional effect of single or multiple amino acid substitutions, insertions and deletions using the prediction tool PROVEAN. The server provides rapid analysis of protein variants from any organisms, and also supports high-throughput analysis for human and mouse variants at both the genomic and protein levels.