Concise Synthesis of the Terpene Core Structure of Suaveolindole through a Time-Economic Route
Concise Synthesis of the Terpene Core Structure of Suaveolindole through a Time-Economic Route
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通过省时路线简洁合成 Suaveolindole 的萜烯核心结构
DOI：
10.1055/a-1707-6593
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发表时间：
2022
期刊：
影响因子：
2
通讯作者：
Kakiuchi Kiyomi
中科院分区：
文献类型：
--
作者：
Tanimoto Hiroki;Tojo Kazuki;Morimoto Tsumoru;Kakiuchi Kiyomi
通过一条简洁的路线合成了杉烷酚萜类核心结构，并节省了时间。一个可扩展的合成路线，从pulegone获得所需的α，β,γ，δ-不饱和酯在短时间内。通过Eschenmoser-Claisen重排，立体选择性地引入了拥挤双烯丙基位置的碳侧链。
The terpene core structure of suaveolindoles was synthesized through a concise route in a time-economical manner. A scalable synthetic route from pulegone delivered the desired α,β,γ,δ-unsaturated ester in a brief period. By way of Eschenmoser–Claisen rearrangement, carbon side-chain moiety at the crowded double-allylic position was introduced stereoselectively.