Cupric ion release controlled by copper/low-density polyethylene nanocomposite in simulated uterine solution
Cupric ion release controlled by copper/low-density polyethylene nanocomposite in simulated uterine solution
复制标题
铜/低密度聚乙烯纳米复合材料在模拟子宫溶液中控制铜离子的释放
DOI：
10.1002/jbm.b.30587
复制
发表时间：
2007-01-01
影响因子：
3.4
通讯作者：
Xie, Changsheng
中科院分区：
文献类型：
--
作者：
Cai, Shuizhou;Xia, Xianping;Xie, Changsheng
研究了新型铜/低密度聚乙烯复合材料宫内节育器材料在模拟宫腔液中的Cu2+释放速率。用X射线衍射法对这些复合材料的腐蚀产物进行了鉴定。用内标法测定了铜相和氧化亚铜在不同腐蚀深度下的分布。作为对比，将两种大小的铜颗粒嵌入到聚乙烯基质中形成复合材料。纳米复合材料的平均铜粒径为30em，微米复合材料的平均铜粒径为52gm。纳米复合材料控制Cu2+释放的机理表明，场发射扫描电子显微镜观察到纳米复合材料中有许多由铜纳米颗粒组成的团簇，导致了大量Cu2O的形成，从而促进了Cu2+的稳定释放。利用扫描电子显微镜和能量色散X射线微区分析技术(SEM/EDX)测量了纳米复合材料的腐蚀深度，并计算了复合材料的寿命。结果表明，纳米复合材料的Cu2+释放行为明显优于微米复合材料。(C)2006年威利期刊公司。
The Cu2+ release rate of novel copper/low-density polyethylene composites as an intrauterine device material in the simulated uterine solution was investigated for 280 days. The corrosion products of these composites were identified by the X-ray diffraction method. The distributions of the copper phase and the cuprous oxide phase at different corrosion depths in the composites were measured by the internal standard method. For comparison, copper particles of two sizes were embedded in a polyethylene matrix to form composites. The average copper particle diameter of the nanocomposite was 30 em, while that of microcomposite was 52 gm. Mechanism of Cu2+ release controlled by the nanocomposite revealed that many clusters composed of copper nanoparticles, which were observed by the field emission scanning electron microscopy in the nanocomposite, led to the formation of large amounts of Cu2O and consequently facilitated the Cu2+ steady release. A scanning electron microscope with energy dispersive X-ray microanalysis mapping technique (SEM/EDX) was employed to measure the corrosion depth and to calculate the life span of the nanocomposite. The result that the nanocomposite displayed a near zero-order release after a month of incubation indicated that the Cu2+ release behavior controlled by nanocomposite was remarkably superior to that by microcomposite. (c) 2006 Wiley Periodicals, Inc.