Impact of reduced left atrial functions on diagnosis of paroxysmal atrial fibrillation: Results from analysis of time-left atrial volume curve determined by two-dimensional speckle tracking
Impact of reduced left atrial functions on diagnosis of paroxysmal atrial fibrillation: Results from analysis of time-left atrial volume curve determined by two-dimensional speckle tracking
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DOI：
10.1016/j.jjcc.2010.08.006
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发表时间：
2011-01-01
影响因子：
2.5
通讯作者：
Kitakaze, Masafumi
中科院分区：
文献类型：
--
作者：
Mori, Mika;Kanzaki, Hideaki;Kitakaze, Masafumi
背景：心房颤动通常与左心房（LA）的储血和升压功能受损有关。二维散斑追踪技术（2DST）的最新进展，使自动分析的时间LA容积曲线代表这些功能。目的：应用二维超声心动图（2DST）评价阵发性心房颤动（PAF）患者左心房功能。方法：对111例（男性68例，年龄62 ± 16岁）阵发性房颤（PAF）患者（53例）和非阵发性房颤（PAF）患者（58例）进行研究。根据心尖四腔和二腔视图（iE 33，Philips with QLAB 6.0，Philips Medical Systems，博瑟尔，WA，USA）构建时间-LA容积曲线后，获得最大LA容积（LAVmax）、房前收缩LA容积（LAVpreA）和最小LA容积（LAVmin）。结果：PAF组LAVmax为80 ± 21 ml，对照组为65 ± 16 ml，两组比较差异有统计学意义（P < 0.05），两组比较差异有统计学意义（P < 0.05）。
Background: Atrial fibrillation is commonly associated with impaired reservoir and booster functions of the left atrium (LA). Recent advances in two-dimensional speckle tracking technique (2DST) enabled automatic analysis of the time-LA volume curve representing these functions. Our objective was to evaluate LA function in patients with or without paroxysmal atrial fibrillation (PAF) using 2DST.Methods: We studied 111 patients (68 men, age 62 +/- 16 years) with (n=53) or without (n=58) PAF. After constructing time-LA volume curves from the apical four and two chamber views (iE33, Philips with QLAB 6.0, Philips Medical Systems, Bothell, WA, USA), maximal LA volume (LAVmax), preatrial contraction LA volume (LAVpreA), and minimum LA volume (LAVmin) were obtained. Then, LA reservoir volume (ARV=LAVmax-LAVmin) and active emptying volume (AEV=LAVpreA-LAVmin) were calculated to determine ARV/LAVmax as reservoir function and AEV/LAVpreA as booster pump function.Results: PAF was associated with greater LAVmax than that in controls (80 +/- 21 ml versus 65 +/- 16 ml, p