Ophiocerins A-D and ophioceric acid: tetrahydropyran derivatives and an africane sesquiterpenoid from the freshwater aquatic fungus Ophioceras venezuelense.
Ophiocerins A-D and ophioceric acid: tetrahydropyran derivatives and an africane sesquiterpenoid from the freshwater aquatic fungus Ophioceras venezuelense.
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DOI：
10.1021/np050035i
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发表时间：
2005-04
影响因子：
5.1
通讯作者：
Ricardo F Reátegui;J. Gloer;Jinx Campbell;C. Shearer
中科院分区：
文献类型：
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作者：
Ricardo F Reátegui;J. Gloer;Jinx Campbell;C. Shearer
从水生真菌 Ophioceras venezuelense 的培养物中分离出了四种新的四氢吡喃衍生物，称为蛇柏素 A-D (1-4) 和一种新的非洲倍半萜类化合物（蛇柏酸；5），以及已知的化合物 regiolone。通过分析 1D 和 2D NMR 数据确定了这些化合物的结构和相对立体化学，同时通过应用激子手性 CD 方法提出了 1-4 的绝对立体化学归属。
Four new tetrahydropyran derivatives called ophiocerins A-D (1-4) and a new africane sesquiterpenoid (ophioceric acid; 5) have been isolated from cultures of the aquatic fungus Ophioceras venezuelense, together with the known compound regiolone. The structures and relative stereochemistry of these compounds were determined by analysis of 1D and 2D NMR data, while absolute stereochemical assignments for 1-4 were proposed by application of the exciton chirality CD method.