Influence of pupil and optical zone diameter on higher-order aberrations after wavefront-guided myopic LASIK
Influence of pupil and optical zone diameter on higher-order aberrations after wavefront-guided myopic LASIK
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DOI：
10.1016/j.jcrs.2005.10.023
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发表时间：
2005-12-01
影响因子：
2.8
通讯作者：
Kohnen, T
中科院分区：
文献类型：
--
作者：
Bühren, J;Kühne, C;Kohnen, T
目得：目的：探讨波前像差引导准分子激光原位角膜磨镶术（LASIK）术后瞳孔直径和光学区直径对高阶像差的影响。平均术前等效球镜为-6.86屈光度（D）+/- 1.24（SD）（范围-4.25至-9.5 D）;平均计划OZ直径为6.26 +/- 0.45 mm（范围5.7至7.1 mm）。所有患者均顺利接受波前引导LASIK（Zyoptix 3.1版，博士伦），随访12个月。在术前和LASIK术后12个月，使用Hartmann-Shack传感器在最大瞳孔散大时进行波前测量。对于个体OZ直径和个体散瞳PD（7.93 +/-0.46 mm），计算3.0、3.5、4.0、5.0、6.0和7.0 mm的瞳孔直径（PD）的波前误差。瞳孔直径和OZ直径之间的关系（清除率分数[FC]）对HOA的影响进行了描述和量化使用曲线回归与四阶多项式fit.Results：有一个可重复的FC和诱导HOA的量之间的关系。HOA均方根和初级球差（Z（4）（0））的变化与FC显著相关。如果OZ比瞳孔大16.5%（FC = 1.17），则预期仅诱导出OZ等于瞳孔时一半的HOA量。相比之下，OZ比瞳孔小9%（FC = 0.91）导致HOA诱导比FC = 1时高50%。结论：OZ区与瞳孔比（清除率）对波前引导LASIK术后HOA诱导有显著影响。
PURPOSE: To investigate the influence of pupil and optical zone (OZ) diameter on higher-order aberrations (HOAs) after myopic wavefront-guided laser in situ keratomileusis (LASIK).METHODS: Twenty-seven myopic eyes of 19 patients were included. The mean preoperative spherical equivalent was -6.86 diopters (D) +/- 1.24 (SD) (range -4.25 to -9.5 D); the mean planned OZ diameter was 6.26 +/- 0.45 mrn (range 5.7 to 7.1 mm). All patients had uneventful wavefront-guided LASIK (Zyoptix version 3.1, Bausch & Lomb) and an uncomplicated follow-up of 12 months. Wavefront measurements were performed with a Hartmann-Shack sensor in maximum mydriasis preoperatively and 12 months after LASIK. Wavefront errors were computed for pupil diameters (PDs) of 3.0, 3.5, 4.0, 5.0, 6.0, and 7.0 mm for the individual OZ diameter and for the individual mydriatic PD (7.93 +/- 0.46 mm). The impact of the relationship between pupil diameter and OZ diameter (fractional clearance [FC]) on HOA was described and quantified using curvilinear regression with a 4th-order polynomial fit.RESULTS: There was a reproducible relationship between FC and the amount of induced HOA. The change in HOA root mean square and primary spherical aberration (Z(4)(0)) was significantly correlated with FC. If the OZ was 16.5% larger than the pupil (FC = 1.17), only half the amount of HOA was expected to be induced than if the OZ equaled the pupil. In contrast, an OZ that was 9% smaller than the pupil (FC = 0.91) resulted in an HOA induction 50% higher than at FC = 1.CONCLUSION: The OZ zone to pupil ratio (fractional clearance) had a significant impact on HOA induction after wavefront-guided LASIK.