Amino-Acid-Based Zwitterionic Polymer and Its Cu(II)-Induced Aggregation into Nanostructures: A Template for CuS and CuO Nanoparticles
Amino-Acid-Based Zwitterionic Polymer and Its Cu(II)-Induced Aggregation into Nanostructures: A Template for CuS and CuO Nanoparticles
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DOI：
10.1002/marc.201300481
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发表时间：
2013-09-01
影响因子：
4.6
通讯作者：
Mandal, Tarun K.
中科院分区：
文献类型：
--
作者：
Banerjee, Sanjib;Maji, Tanmoy;Mandal, Tarun K.
描述了一种方便的水基方法，用于合成基于 L-赖氨酸的两性离子聚合物聚（ε-L-赖氨酰丙烯酰胺）（PLAM），无需使用保护基化学、色谱纯化和有机溶剂作为反应介质。 PLAM 在每个重复单元中都含有胺基和羧酸基团，只需改变溶液的 pH 值即可质子化或去质子化以获得整体正电荷或负电荷。 PLAM 作为两性离子聚合物缓冲剂在水中的适用性经过测试。研究了 Cu(II) 离子诱导的 PLAM 聚集作为溶液 pH 值的函数。由于 PLAM 通过与 Cu(II) 离子络合而聚集，因此在 pH 9.5 时形成球形纳米凝胶聚集体。球形聚集体似乎通过在 pH < 5.5 时破坏络合而解离，导致 PLAM 分子溶解。该聚集过程是 pH 可逆的。 Cu(II)-PLAM 聚集体用作制造 CuO 和 CuS 纳米颗粒的模板。
A convenient and water-based approach is described for the synthesis of an l-lysine-based zwitterionic polymer, poly(epsilon-l-lysinyl acrylamide) (PLAM), without using protecting group chemistry, chromatographic purifications, and organic solvents as the reaction media. PLAM contains both amine and carboxylic acid groups in each repeating unit, which can either be protonated or deprotonated just by altering the pH of the solution to obtain overall positive or negative charge. PLAM is tested for its applicability as a zwitterionic polymeric buffer in water. Cu(II) ion-induced aggregation of PLAM as a function of solution pH is studied. Spherical nanogel aggregates are formed at pH 9.5 due to aggregation of PLAM through its complexation with Cu(II) ion. Spherical aggregates appear to dissociate via breaking of the complexation at a pH < 5.5 resulting in molecular dissolution of PLAM. This aggregation process is pH reversible. The Cu(II)-PLAM aggregates are used as a template for fabrication of CuO and CuS nanoparticles.