CHEMICAL AND PHYSICOCHEMICAL STUDIES ON THE MINERAL-DEPOSITS OF THE HUMAN ATHEROSCLEROTIC AORTA
CHEMICAL AND PHYSICOCHEMICAL STUDIES ON THE MINERAL-DEPOSITS OF THE HUMAN ATHEROSCLEROTIC AORTA
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DOI：
10.1016/0021-9150(80)90005-2
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发表时间：
1980-01-01
期刊：
影响因子：
5.3
通讯作者：
BINETTE, JP
中科院分区：
文献类型：
--
作者：
SCHMID, K;MCSHARRY, WO;BINETTE, JP
采用一种新的方法制备了人动脉粥样硬化主动脉的矿物沉积物，其特点是使用温和的条件。从动脉粥样硬化斑块中分离出大小矿物质沉积物，其化学成分基本相同。沉积物主要由钙磷灰石（71%）、碳酸盐（9%）组成，并含有相对高百分比的蛋白质（15%）。X射线衍射图分析显示存在平均尺寸为λ的微晶。0.1μ m。电子探针分析表明，矿物存款的表面和内部具有相同的化学成分。扫描电子显微镜显示，沉积物是不均匀的，由5种结构组成：由球形层组成的表面光滑的球体的个体和聚集体;由纺锤状径向排列的颗粒组成的球体;形成网络和束的纤维，有时包括球形颗粒;具有模糊表面的不规则形状的颗粒;以及具有光滑表面的平板。
The mineral deposits of the human atherosclerotic aorta were prepared by a new method characterized by the use of mild conditions. Large and small mineral deposits were isolated from the atherosclerotic plaque and possessed essentially the same chemical composition. The deposits consisted mainly of calcium apatite (71%), carbonate (9%) and contained a relatively high percentage of protein (15%). X-ray diffraction pattern analysis revealed the presence of microcrystals with an average size of .apprx. 0.1 .mu.m. Electron probe analysis showed that the surface and interior of the mineral deposit had the same chemical composition. Scanning electron microscopy revealed that the deposits were heterogenous and consisted of 5 structures: individual and conglomerates of smooth-surfaced spheres consisting of spherical layers; spheres consisting of spindle-like, radially arranged particles; fibers forming networks and bundles which sometimes included spherical particles; irregularly shaped particles with fuzzy surfaces; and flat plates with smooth surfaces.