Detection of Wolbachia genes in a patient with non-Hodgkin's lymphoma
Detection of Wolbachia genes in a patient with non-Hodgkin's lymphoma
复制标题
DOI：
10.1016/j.cmi.2014.09.008
复制
发表时间：
2015-02-01
影响因子：
14.2
通讯作者：
Zhang, Y. -Z.
中科院分区：
文献类型：
--
作者：
Chen, X. -P.;Dong, Y. -J.;Zhang, Y. -Z.
5天内在一名高烧患者的血液中两次检测到沃尔巴克氏体16S rRNA和fbpA基因。患者服用氟喹诺酮类药物后发烧消失。四个星期后，他被诊断患有非霍奇金淋巴瘤并接受 R-CHOP（利妥昔单抗、环磷酰胺、阿霉素、长春新碱、泼尼松龙）治疗，病情完全缓解。这是第一份从人类非霍奇金淋巴瘤患者血液中检测到沃尔巴克氏体基因的报告。临床微生物学和感染 (C) 2014 年欧洲临床微生物学和传染病学会。由爱思唯尔有限公司出版。保留所有权利。
Wolbachia 16S rRNA and fbpA genes were twice detected over 5 days in the blood of a patient with high fever. The patient was given fluoroquinolones and the fever resolved. Four weeks later, he was diagnosed with non-Hodgkin's lymphoma and received R-CHOP (Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, Prednisolone) treatment resulting in complete remission. This is the first report of detection of Wolbachia genes from the blood of human patients with non-Hodgkin's lymphoma. Clinical Microbiology and Infection (C) 2014 European Society of Clinical Microbiology and Infectious Diseases. Published by Elsevier Ltd. All rights reserved.