An Empirical Study on Factors Affecting Medication Adherence in Outpatients with Depression: From the Perspective of Medication Support for Patients Using Pharmacies
An Empirical Study on Factors Affecting Medication Adherence in Outpatients with Depression: From the Perspective of Medication Support for Patients Using Pharmacies
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门诊抑郁症患者服药依从性影响因素的实证研究——基于药房患者用药支持的视角
DOI：
10.11256/jjdi.24.17
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发表时间：
2022
期刊：
影响因子：
--
通讯作者：
熊谷 純
中科院分区：
文献类型：
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作者：
櫻井 秀彦;熊谷 純
目的：本研究旨在通过多变量分析阐明影响门诊抑郁症患者用药依从性的因素。方法：于 2018 年 1 月对门诊抑郁症患者进行了一项关于用药依从性、用药态度（Drug Attitude Inventory-10；DAI-10）、用药自我管理以及对处方医生/药房的满意度的网络调查。用药指导的重要性高/低、咨询意向高/低以及咨询频率高/低。结果：对于平均分，根据 t 检验，男性和女性之间没有观察到显着差异。就用药指导的重要性而言，高重要性组的处方医生/药房满意度显着更高，自我管理也更好。在咨询意向方面，咨询意向高的受访者在 DAI-10 上的得分显着更高，自我管理能力更好，处方医生/药房满意度更高。从就诊频率来看，只有高频组的药房满意度显着较高。路径分析显示，一般来说，依从性受到用药态度和自我管理的影响，而处方医生/药房的满意度和自我管理则受到用药态度的影响。在组间比较中，药房满意度并不影响男性或用药指导重要性较低的群体的用药依从性。此外，仅在非咨询组中，用药态度并不影响依从性。讨论：这些结果表明有必要改进药房对抑郁症门诊患者的用药支持措施。此外，为了使改善用药态度和依从性的措施有效，患者需要了解有效使用药剂师的好处和重要性，包括用药支持和咨询，并积极参与维护和促进患者的健康。
Objective: This study aimed to elucidate the factors that affect medication adherence in outpatients with depression using multivariate analysis.Methods: A web-based survey on medication adherence, medication attitude (Drug Attitude Inventory-10; DAI-10), medication self-management, and satisfaction with the prescribing physician/pharmacy for outpatients with depression was conducted in January 2018. T-tests and path analysis were performed to evaluate comparisons of responses based on gender, high/low importance of medication guidance, high/low intention to consult, and high/low frequency of consultations.Results: For mean scores, no significant difference was observed between males and females according to a t-test. In terms of the importance of medication guidance, the high importance group had significantly higher prescribing physician/pharmacy satisfaction and better self-management. In terms of intention to consult, respondents with high intention to consult had significantly higher scores on the DAI-10, better self-management, and higher prescribing physician/pharmacy satisfaction. In terms of frequency of consultations, only pharmacy satisfaction was significantly higher in the high-frequency group. Path analysis revealed that, in general, adherence was influenced by medication attitude and self-management, and prescribing physician/pharmacy satisfaction and self-management were influenced by medication attitude. In the intergroup comparison, pharmacy satisfaction did not affect medication adherence in males or the group with low importance of medication guidance. In addition, medication attitude did not affect adherence only in the non-consultation group.Discussion: These results suggest that it is necessary to improve the medication support measures at pharmacies for outpatients with depression. Furthermore, in order for the measures to improve medication attitudes and adherence to be effective, it is necessary for patients to understand the benefits and importance of using pharmacists effectively, including medication support and consultation, and to be actively involved in the maintenance and promotion of patients' health.