Explaining risk factors for drug-resistant tuberculosis in England and Wales: contribution of primary and secondary drug resistance
Explaining risk factors for drug-resistant tuberculosis in England and Wales: contribution of primary and secondary drug resistance
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DOI：
10.1017/s0950268804002869
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发表时间：
2004-12-01
影响因子：
4.2
通讯作者：
Watson, JM
中科院分区：
文献类型：
--
作者：
Conaty, SJ;Hayward, AC;Watson, JM
耐药结核病可在治疗过程中传播(原发)或发展(继发)。我们调查了每种耐药的风险因素。我们比较了英格兰和威尔士两个时期(1993-1994年和1998-2000年)所有患有异烟肼和多药耐药结核病的患者与完全敏感的结核病患者，分别检查了没有和有过结核病史的患者(原发和继发耐药结核病的替代物)。以前有肺结核涂片阳性和抵达英国的患者
Drug-resistant tuberculosis can be transmitted (primary) or develop during the course of treatment (secondary). We investigated risk factors for each type of resistance. We compared all patients in England and Wales with isoniazid- and multidrug-resistant tuberculosis in two time-periods (1993-1994 and 1998-2000) with patients with fully sensitive tuberculosis, examining separately patients without and with previous tuberculosis (a proxy for primary and secondary drug-resistant tuberculosis). Patients with previous tuberculosis smear positivity and arrival in the United Kingdom