Fast colorimetric sensing of adenosine and cocaine based on a general sensor design involving aptamers and nanoparticles

Fast colorimetric sensing of adenosine and cocaine based on a general sensor design involving aptamers and nanoparticles
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DOI:
10.1002/anie.200502589
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发表时间:
2006-01-01
影响因子:
16.6
通讯作者:
Lu, Y
Lu, Y
中科院分区:
化学1区
文献类型:
--
作者:
Liu, JW;Lu, Y

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易于改变颜色:DNA适体已被用于组装DNA功能化的金纳米颗粒,以产生高灵敏度和选择性的比色传感器,在添加底物时具有瞬时颜色响应。一般的方法已经显示了腺苷和可卡因(见图片),但应适用于任何适体的选择。(图中所示)。
Apt to change color: DNA aptamers have been used to assemble DNA-functionalized gold nanoparticles to produce highly sensitive and selective colorimetric sensors with an instantaneous color response on addition of a substrate. The general method has been shown for adenosine and cocaine (see picture), but should be applicable to any aptamer of choice.(Figure Presented).