Regulating action: alternating activation of midline frontal and motor cortical networks
Regulating action: alternating activation of midline frontal and motor cortical networks
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DOI：
10.1016/s1388-2457(01)00559-4
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发表时间：
2001-07-01
影响因子：
4.7
通讯作者：
Tucker, DM
中科院分区：
文献类型：
--
作者：
Luu, P;Tucker, DM
目的：研究发现，记录在中线前额叶皮层上的局灶性电场可以指示快速评估决策，包括识别在快速反应任务中犯了错误。这些电场的性质，以及它们是如何与参与响应execution.Methods：作为主题进行了一个快速响应任务的EEG记录与128通道传感器阵列的皮层区域仍有待澄清。通过过滤掉大的慢波的事件相关电位，我们发现，错误相关的负波（Ne/ERN）来自中线额叶振荡，交替振荡的外侧感觉运动皮层。电源分析被用来确定在这些occurrence.Results的产生所涉及的大脑源：结果表明，中线和横向振荡有一个周期约为200毫秒（θ），他们是正确的和错误的反应。当产生错误时，中线错误振荡被强烈地招募，并且它变得与电机振荡相关。源分析本地化的中线错误振荡到中央额叶皮层和横向振荡到sensorimotor cortics.Conclusions：由于在本研究中观察到的中线振荡和额叶中线θ之间的相似性，NE/ERN的性质可以澄清由额叶中线θ文献。中线和感觉运动振荡之间的相关性表明了一种可能的机制，中线额叶评价和监测网络有助于行动调节。(C)2001爱思唯尔科学爱尔兰有限公司保留所有权利。
Objectives: Focal electrical fields recorded over the midline prefrontal cortex have been found to index rapid evaluative decisions, including the recognition of having made an error in a speeded response task. The nature of these electrical fields and how they are related to cortical areas involved in response execution remains to be clarified.Methods: As subjects performed a speeded response task the EEG was recorded with a 128-channel sensor array. By filtering out the large slow waves of the event-related potential, we found that the error-related negativity (Ne/ERN) arises from a midline frontal oscillation that alternates with oscillations over lateral sensorimotor cortex. Electrical source analyses were used to determine the brain sources involved in the generation of these oscillations.Results: The results show that the midline and lateral oscillations have a period of about 200 ms (theta), and they are present for both correct and error responses. When an error is made, the midline error oscillation is recruited strongly, and it becomes correlated with the motor oscillation. Source analyses localized the midline error oscillation to centromedial frontal cortex and the lateral oscillation to sensorimotor cortices.Conclusions: Because of the similarity between the midline oscillation observed in the present study and frontal midline theta, the nature of the Ne/ERN may be clarified by the frontal midline theta literature. The correlation between the midline and sensorimotor oscillations suggests a possible mechanism for how midline frontal evaluative and monitoring networks contribute to action regulation. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.