DAMAGE TO RED-BLOOD-CELLS INDUCED BY ACOUSTIC CAVITATION
DAMAGE TO RED-BLOOD-CELLS INDUCED BY ACOUSTIC CAVITATION
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DOI：
10.1016/0301-5629(94)00089-1
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发表时间：
1995-01-01
影响因子：
2.9
通讯作者：
PRICE, DJ
中科院分区：
文献类型：
--
作者：
DANIELS, S;KODAMA, T;PRICE, DJ
这项实验研究揭示了红细胞的损伤，这是定量相关的声压在照射过程中与0.75 MHz的连续波超声波，使用的强度范围可比的超声波理疗设备（0.25至7 W cm（-2）的空间平均时间平均）。通过使用UV/维斯分光光度计测量溶血程度来研究对红细胞的损伤。有一个明确的相关性之间的量的血红蛋白释放和强度的谐波发射记录从样品在照射过程中。在没有声场的情况下，温度升高不能产生所观察到的溶血程度。这表明损坏是声气穴的直接结果。
This experimental study has revealed damage to red blood cells that is quantitatively related to the acoustic pressure during irradiation with 0.75-MHz continuous-wave ultrasound, using a range of intensities comparable to those employed by ultrasonic physiotherapy equipment (0.25 to 7 W cm(-2) spatial average temporal average). Damage to the red blood cells was investigated by measuring the extent of haemolysis using a UV/VIS spectrophotometer. There was a clear correlation between the amount of haemoglobin released and the intensity of harmonic emissions recorded from the sample during irradiation. The observed degree of haemolysis could not be produced by temperature rises in the absence of the sound field. This suggests that the damage was a direct result of acoustic cavitation.