Genetic Control Of Malaria Mosquitoes.
Genetic Control Of Malaria Mosquitoes.
复制标题
DOI：
10.1016/j.pt.2016.01.002
复制
发表时间：
2016-03
影响因子：
9.6
通讯作者：
Jacobs-Lorena M
中科院分区：
文献类型：
--
作者：
McLean KJ;Jacobs-Lorena M
证明转基因蚊子载体以削弱其传播疟原虫能力的可行性的实验已经知道了十多年。然而，将抗性或种群控制基因传播到野生蚊子种群中的方法仍然是一个未解决的挑战。最近的两份报告给了人们希望，CRISPR技术可能会克服这一挑战。
Experiments demonstrating the feasibility of genetically modifying mosquito vectors to impair their ability to transmit the malaria parasite have been known for well over a decade. However, means to spread resistance or population control genes into wild mosquito populations remains an unsolved challenge. Two recent reports give hope that CRISPR technology may allow such challenge to be overcome.