Study of the association between blood types and breast cancer among Isfahanian women with breast cancer.
Study of the association between blood types and breast cancer among Isfahanian women with breast cancer.
复制标题
DOI：
10.4103/2277-9175.125749
复制
发表时间：
2014-01-01
影响因子：
1
通讯作者：
Nourian, Sayed Mohammad
中科院分区：
文献类型：
--
作者：
Flavarjani, Amir Hossein Mirlohi;Hedayatpour, Behnood;Nourian, Sayed Mohammad
背景：以往的研究表明ABO血型与乳腺癌风险之间可能存在关联。本研究的目的是探讨乳腺癌和ABO和Rh血型之间可能存在的关联。材料与方法：549名妇女，包括173例病例和376名对照。病例组包括乳腺癌患者，所有患者均确诊为癌症。对照组包括没有乳腺癌报告的妇女。对所有病例进行血型采样。结果：ABO（Rh）血型与乳腺癌无明显相关性，ABO（Rh）血型与乳腺癌无明显相关性。浸润性导管内癌的发生率为85%（P > 0.05）。病例组中约5%的诊断癌症被分配到模块化癌，浸润性小叶癌和佩吉特病。这三种类型的癌症在特定血型中没有相对频率。ABO（Rh）血型与乳腺癌类型无明显相关性（P = 0.2）。结论：根据本研究结果，三种类型的乳腺癌在特定血型中无相对频率，血型不能作为乳腺癌的危险因素。
BACKGROUND: Previous studies suggest a possible association between ABO blood group and the risk of breast cancer. The aim of this study is to investigate the presence of a possible association between breast cancer and blood groups ABO and Rh.MATERIALS AND METHODS: 549 women including 173 cases and 376 controls were selected. The case group included patients with breast cancer and the cancer diagnosis was confirmed for all of them. The control group included women with no reports of breast cancer. Blood group sampling of all cases was performed. The obtained information regarding presence or absence of cancer, blood type, age group and type of cancer were analyzed.RESULTS: There is no significant association between blood types ABO (Rh) and the breast cancer. (P > 0.05) It has been found that the prevalence of invasive intraductal carcinoma was 85% among the cases. About 5% of the total diagnosed cancers in the case group were allocated to modularly carcinoma, invasive lobular carcinoma and Paget's disease. There was no relative frequency in specific blood group for these three types of cancer. The blood types ABO (Rh) and breast cancer type showed no significant relation (P = 0.2).CONCLUSION: According to the obtained results from this study, there was no relative frequency in specific blood group for these three types of cancer and the blood type could not be influenced as a risk factor in breast cancer.