CT-Definable Subtypes of Chronic Obstructive Pulmonary Disease: A Statement of the Fleischner Society
CT-Definable Subtypes of Chronic Obstructive Pulmonary Disease: A Statement of the Fleischner Society
复制标题
DOI：
10.1148/radiol.2015141579
复制
发表时间：
2015-10-01
期刊：
影响因子：
19.7
通讯作者：
Crapo, James D.
中科院分区：
文献类型：
--
作者：
Lynch, David A.;Austin, John H. M.;Crapo, James D.
本声明的目的是描述和定义慢性阻塞性肺疾病（COPD）受试者中通过计算机断层扫描（CT）图像的目视和定量评价可识别的表型异常，旨在为COPD患者的个性化治疗方法做出贡献。定量CT可用于识别和顺序评估肺气肿性肺破坏的程度、气道壁的变化和呼气潴留。然而，CT扫描的视觉评估对于描述COPD患者肺结构改变的模式仍然很重要。本文提出并说明的分类系统为COPD的视觉和定量评估提供了一种结构化的方法。肺气肿分为小叶中心型（细分为微量、轻度、中度、融合性和晚期破坏性肺气肿）、全小叶型和间隔旁型（细分为轻度或实质性）。其他重要的视觉特征包括气道壁增厚、炎性小气道疾病、气管异常、间质性肺异常、肺动脉增大和支气管扩张。(C)RSNA，2015年
The purpose of this statement is to describe and define the phenotypic abnormalities that can be identified on visual and quantitative evaluation of computed tomographic (CT) images in subjects with chronic obstructive pulmonary disease (COPD), with the goal of contributing to a personalized approach to the treatment of patients with COPD. Quantitative CT is useful for identifying and sequentially evaluating the extent of emphysematous lung destruction, changes in airway walls, and expiratory air trapping. However, visual assessment of CT scans remains important to describe patterns of altered lung structure in COPD. The classification system proposed and illustrated in this article provides a structured approach to visual and quantitative assessment of COPD. Emphysema is classified as centrilobular (subclassified as trace, mild, moderate, confluent, and advanced destructive emphysema), panlobular, and paraseptal (subclassified as mild or substantial). Additional important visual features include airway wall thickening, inflammatory small airways disease, tracheal abnormalities, interstitial lung abnormalities, pulmonary arterial enlargement, and bronchiectasis. (C) RSNA, 2015