Citywide Control of Aedes aegypti (Diptera: Culicidae) during the 2016 Zika Epidemic by Integrating Community Awareness, Education, Source Reduction, Larvicides, and Mass Mosquito Trapping
Citywide Control of Aedes aegypti (Diptera: Culicidae) during the 2016 Zika Epidemic by Integrating Community Awareness, Education, Source Reduction, Larvicides, and Mass Mosquito Trapping
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DOI：
10.1093/jme/tjz009
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发表时间：
2019-07-01
影响因子：
2.1
通讯作者：
Waterman, Stephen H.
中科院分区：
文献类型：
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作者：
Barrera, Roberto;Harris, Angela;Waterman, Stephen H.
在2016年疫情期间，为控制波多黎各卡瓜斯市的埃及伊蚊和寨卡病毒传播，开展了这项调查，采用综合媒介管理（IVM），包括社区意识和教育、减少传染源、杀幼虫和使用自杀妊娠诱蚊器（AGO）进行大规模诱捕。疫情在2016年8月至10月达到高峰，2017年4月后减弱。2016年10月/ 11月为预干预期，IVM持续至2017年8月。接受治疗的地区（23.1公里(2)）有61,511名居民和25,363座建筑物。城市被划分为8个偶数集群，并按照集群随机楔形设计进行处理。我们分析了雌伊蚊群。每周使用360次AGO监测陷阱检测登革热（DENV）、基孔肯雅（CHIKV）和寨卡病毒（ZIKV）的RNA。在每个集群中监测降雨量、温度和相对湿度。蚊密度显著变化（广义线性混合模型；F-8,F- 14,F-588 = 296; P < 0.001），从干预前的8.0 +/- 0.1只/周增加到60%后的2.1 +/- 0.04只/周，覆盖率在80%以上时增加到1.4 +/- 0.04只/周。2016年10月至2017年3月，在总共12081个蚊池中，有1个DENV-， 7个CHIKV-和49个zikv -阳性池。之后，我们在2017年7月只发现了一个DENV阳性池。这项调查表明，有可能扩大有效的Ae。通过IVM控制埃及伊蚊到一个中等城市，其中包括大规模捕获重力伊蚊。蚊雌性。
This investigation was initiated to control Aedes aegypti and Zika virus transmission in Caguas City, Puerto Rico, during the 2016 epidemic using Integrated Vector Management (IVM), which included community awareness and education, source reduction, larviciding, and mass-trapping with autocidal gravid ovitraps (AGO). The epidemic peaked in August to October 2016 and waned after April 2017. There was a preintervention period in October/November 2016 and IVM lasted until August 2017. The area under treatment (23.1 km(2)) had 61,511 inhabitants and 25,363 buildings. The city was divided into eight even clusters and treated following a cluster randomized stepped-wedge design. We analyzed pools of female Ae. aegypti adults for RNA detection of dengue (DENV), chikungunya (CHIKV), and Zika (ZIKV) viruses using 360 surveillance AGO traps every week. Rainfall, temperature, and relative humidity were monitored in each cluster. Mosquito density significantly changed (generalized linear mixed model; F-8,F- 14,F-588 = 296; P < 0.001) from 8.0 +/- 0.1 females per trap per week before the intervention to 2.1 +/- 0.04 after the percentage of buildings treated with traps was 60% and to 1.4 +/- 0.04 when coverage was above 80%. Out of a total 12,081 mosquito pools, there were 1 DENV-, 7 CHIKV-, and 49 ZIKV-positive pools from October 2016 to March 2017. Afterward, we found only one positive pool of DENV in July 2017. This investigation demonstrated that it was possible to scale up effective Ae. aegypti control to a medium-size city through IVM that included mass trapping of gravid Ae. aegypti females.